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Seizures and Epilepsy in African Grey Parrots

Bird · Psittacus erithacus · typical adult weight 0.40–0.65 kg

9 cited drugs treat Seizures and Epilepsy in african grey parrots: Calcium (oral/injectable), Calcium Gluconate, Clonazepam, Diazepam, Levetiracetam, Magnesium Sulfate, Midazolam, Midazolam Injectable, Zonisamide.

Acute control and chronic management of seizure disorders. Status-epilepticus protocols use benzodiazepines first line, with phenobarbital, levetiracetam, or potassium bromide for maintenance. Etiology workup is essential — idiopathic epilepsy is a diagnosis of exclusion.

The overview above describes Seizures and Epilepsy across species; the citations below are the ExoticRx dose rules scoped to african grey parrots — a reference list, not new species-specific clinical guidance.

Calcium (oral/injectable)(Cal-Phos, Calciquid)

Supplement
RouteDoseFrequencyDurationIndicationEvidenceSource
IV50–100 mg/kgonceSlow IV; transition to oralAcute hypocalcemia with seizuresModerateBeynon PH, Forbes NA, Lawton MP.C. Manual of Psittacine Birds, Iowa State University Press, Ames, IA; 1996. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.475 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
RouteDoseFrequencyDurationIndicationEvidenceSource
IM50–100 mg/kgnot stated in sourceEmergency; follow with oralAcute hypocalcemia, seizuresModerateHuckabee JR. Raptor therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:91-116.; Huff DG. Avian fluid therapy and nutritional therapeutics. Semin Avian Exot Pet Med. 1993;2:13-16.; Ritchie BW, Harrison GJ. Formulary. In: Ritchie BW, Harrison GJ, Harrison LR, eds. Avian Medicine: Principles and Application; Wingers Publishing, Lake Worth, FL; 1994:457-478. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.475 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Clonazepam

Neurological
RouteDoseFrequencyIndicationEvidenceSource
PO0.5 mg/kgq12hAntiepilepticModerate73. Beaufrère H, Nevarez J, Gaschen L, et al. Diagnosis of presumed acute ischemic stroke and associated seizure management in a Congo African grey parrot. J Am Vet Med Assoc. 2011;239(1):122-128. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.472 doi:10.2460/javma.239.1.122 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.10 (Psychotropic and Antiepileptic Agents Used in Birds.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Diazepam(Valium)

Sedative
RouteDoseFrequencyDurationIndicationEvidenceSource
IM0.5–1.5 mg/kgq8-12hEmergencyControl of seizuresExtrapolatedDelk K. Clinical management of seizures in avian patients. J Exot Pet Med. 2012;21(2):132-139. doi:10.1053/j.jepm.2012.02.014 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.472 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 5.10 (Psychotropic and Antiepileptic Agents Used in Birds.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Levetiracetam(Keppra)

Anticonvulsant
RouteDoseFrequencyIndicationEvidenceSource
PO50–100 mg/kgq8hLong-term seizure managementModerate73. Beaufrère H, Nevarez J, Gaschen L, et al. Diagnosis of presumed acute ischemic stroke and associated seizure management in a Congo African grey parrot. J Am Vet Med Assoc. 2011;239(1):122-128. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.473 doi:10.2460/javma.239.1.122 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.10 (Psychotropic and Antiepileptic Agents Used in Birds.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Magnesium Sulfate(MgSO4, Epsom Salt)

Emergency
RouteDoseFrequencyIndicationEvidenceSource
IM20 mg/kgonceDietary hypomagnesaemia and seizuresModerate478. Kirchgessner MS, Tully TN, Nevarez J, et al. Magnesium therapy in a hypocalcemic African grey parrot (Psittacus erithacus). J Avian Med Surg. 2012;26(1):17-21. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.476 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.11 (Nutritional/Mineral Support and Supplementation Used in Birds). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — CORROBORATED 2026-08-06 by independent literature: Magnesium therapy in a hypocalcemic African grey parrot (Psittacus erithacus). (Journal of avian medicine and surgery, 2012). doi:10.1647/2009-021.1. https://doi.org/10.1647/2009-021.1. The paper reports this drug at this dose in this species: "upplementation for 4 days. Baseline magnesium levels in this parrot were determined to be 1.9 […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Midazolam(Versed)

Anesthetic
RouteDoseFrequencyDurationIndicationEvidenceSource
IV0.5–1 mg/kgonceEmergencySeizure controlModerateAbou-Madi N. Avian anesthesia. Vet Clin North Am Exot Anim Pract. 2001;4:147-167. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.454 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 5.5 (Chemical Restraint/Anesthetic/Sedative/Analgesic Agents Used in Birds.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Midazolam Injectable(Versed)

Neurological
RouteDoseFrequencyDurationIndicationEvidenceSource
IM0.5–2 mg/kgIMAs neededSedation, seizuresModerateAbou-Madi N. Avian anesthesia. Vet Clin North Am Exot Anim Pract. 2001;4:147-167. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.454 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 5.5 (Chemical Restraint/Anesthetic/Sedative/Analgesic Agents Used in Birds.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Zonisamide(Zonegran)

Anticonvulsant
RouteDoseFrequencyIndicationEvidenceSource
PO20 mg/kgq8-12hAnti-seizureModerate73. Beaufrère H, Nevarez J, Gaschen L, et al. Diagnosis of presumed acute ischemic stroke and associated seizure management in a Congo African grey parrot. J Am Vet Med Assoc. 2011;239(1):122-128. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.474 doi:10.2460/javma.239.1.122 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.10 (Psychotropic and Antiepileptic Agents Used in Birds.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.

Seizures and Epilepsy in African Grey Parrots: 9 Cited Drug Options | ExoticRx