Fish · Cyprinus carpio · typical adult weight 0.25–20.00 kg
Acyclovir is dosed at 10 mg/kg Intracoelomic (ICe) single dose in koi, per Quijano Carde EM, Yazdi Z, Yun S, Hu R, Knych H, Imai DM, Soto E. Pharmacokinetic and Efficacy Study of Acyclovir Against Cyprinid Herpesvirus 3 in Cyprinus carpio. Front Vet Sci. 2020;7:587952. Acyclovir is used in koi for Koi herpesvirus (cyprinid herpesvirus 3) outbreak — reduction of mortality. Routes documented in koi: Intracoelomic (ICe). A typical adult koi weighs 0.25–20.00 kg. ExoticRx lists 1 cited dose rule for Acyclovir in koi, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zovirax
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| Intracoelomic (ICe) | 10 mg/kg | single dose | Koi herpesvirus (cyprinid herpesvirus 3) outbreak — reduction of mortality | Strong | Quijano Carde EM, Yazdi Z, Yun S, Hu R, Knych H, Imai DM, Soto E. Pharmacokinetic and Efficacy Study of Acyclovir Against Cyprinid Herpesvirus 3 in Cyprinus carpio. Front Vet Sci. 2020;7:587952. doi:10.3389/fvets.2020.587952 https://pmc.ncbi.nlm.nih.gov/articles/PMC7642461/ |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10 | ICE | Carpenter's Exotic Animal Formulary, 6th edTable 2.1 | 10 mg/kg ICe |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
Typical range: 0.25–20 kg
If provided, volume will be calculated alongside dose.
Reference only. Verify against current literature before clinical use.
Nucleoside analog selectively phosphorylated by viral thymidine kinase. Inhibits viral DNA polymerase. Active against herpesviruses.
Used for equine herpesvirus and some avian herpesviruses. Limited efficacy for FHV-1 in cats (famciclovir preferred). Nephrotoxicity with IV form — ensure hydration. Crystalluria.
Species-specific contraindications and adverse-reaction reports for koi may differ from canine / feline reference data — consult the primary citations listed with each rule.
Acyclovir dose range in koi, with cited source references: Intracoelomic (ICe) 10 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Acyclovir in koi: Intracoelomic (ICe).
Acyclovir is indicated in koi for: Koi herpesvirus (cyprinid herpesvirus 3) outbreak — reduction of mortality.
These are general warnings for Acyclovir across species; consult the koi dosing table above for species-specific guidance. Used for equine herpesvirus and some avian herpesviruses. Limited efficacy for FHV-1 in cats (famciclovir preferred). Nephrotoxicity with IV form — ensure hydration. Crystalluria.
Why a species-specific page? Acyclovir pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in koi — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.