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Acyclovir for Russian Tortoises

Reptile · Testudo horsfieldii · typical adult weight 0.23–0.91 kg

Acyclovir is dosed at 80–240 mg/kg PO q 8 h or q 24 h; topical cream q 12 h in russian tortoises, per Merck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles. Acyclovir is used in russian tortoises for Antiviral. Routes documented in russian tortoises: PO. A typical adult russian tortoise weighs 0.23–0.91 kg. ExoticRx lists 1 cited dose rule for Acyclovir in russian tortoises, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Zovirax

Dose ranges

RouteDoseFrequencyIndicationEvidenceSource
PO80–240 mg/kgq 8 h or q 24 h; topical cream q 12 hAntiviralWeakMerck Veterinary Manual. Antimicrobial Drugs Used in Reptiles (dosing table). Rahway (NJ): Merck & Co.; accessed 2026. URL: https://www.merckvetmanual.com/multimedia/table/antimicrobial-drugs-used-in-reptiles

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Mechanism of action

Nucleoside analog selectively phosphorylated by viral thymidine kinase. Inhibits viral DNA polymerase. Active against herpesviruses.

Side effects & warnings

Used for equine herpesvirus and some avian herpesviruses. Limited efficacy for FHV-1 in cats (famciclovir preferred). Nephrotoxicity with IV form — ensure hydration. Crystalluria.

Species-specific contraindications and adverse-reaction reports for russian tortoises may differ from canine / feline reference data — consult the primary citations listed with each rule.

Frequently asked questions

What is the dose of Acyclovir for Russian Tortoises?

Acyclovir dose range in russian tortoises, with cited source references: PO 80–240 mg/kg q 8 h or q 24 h; topical cream q 12 h.

How is Acyclovir administered in Russian Tortoises?

Documented routes for Acyclovir in russian tortoises: PO.

What conditions does Acyclovir treat in Russian Tortoises?

Acyclovir is indicated in russian tortoises for: Antiviral.

What are the side effects of Acyclovir in Russian Tortoises?

These are general warnings for Acyclovir across species; consult the russian tortoise dosing table above for species-specific guidance. Used for equine herpesvirus and some avian herpesviruses. Limited efficacy for FHV-1 in cats (famciclovir preferred). Nephrotoxicity with IV form — ensure hydration. Crystalluria.

Acyclovir dosing in other species

Why a species-specific page? Acyclovir pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in russian tortoises — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.