Amphibian · Anaxyrus houstonensis · typical adult weight 0.03–0.09 kg
Alfaxalone is dosed at 12 mg/kg SC Single dose per sedation episode in houston toads, per Lang M, Freeman K, Griffioen J, Cannizzo S, Delaney MA. Comparison of Subcutaneous Alfaxalone and Subcutaneous Alfaxalone-Dexmedetomidine for Sedation in the Houston Toad (Anaxyrus houstonensis). J Zoo Wildl Med. 2024;55(1). doi:10.1638/2023-0013 https://bioone.org/journals/journal-of-zoo-and-wildlife-medicine/volume-55/issue-1/2023-0013/COMPARISON-OF-SUBCUTANEOUS-ALFAXALONE-AND-SUBCUTANEOUS-ALFAXALONEDEXMEDETOMIDINE-FOR-SEDATION-IN/10.1638/2023-0013.full. Alfaxalone is used in houston toads for Sedation for handling, examination and minor procedures. Routes documented in houston toads: SC. A typical adult houston toad weighs 0.03–0.09 kg. ExoticRx lists 1 cited dose rule for Alfaxalone in houston toads, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Alfaxan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 12 mg/kg | Single dose per sedation episode | Sedation for handling, examination and minor procedures | Moderate | Lang M, Freeman K, Griffioen J, Cannizzo S, Delaney MA. Comparison of Subcutaneous Alfaxalone and Subcutaneous Alfaxalone-Dexmedetomidine for Sedation in the Houston Toad (Anaxyrus houstonensis). J Zoo Wildl Med. 2024;55(1). doi:10.1638/2023-0013 https://bioone.org/journals/journal-of-zoo-and-wildlife-medicine/volume-55/issue-1/2023-0013/COMPARISON-OF-SUBCUTANEOUS-ALFAXALONE-AND-SUBCUTANEOUS-ALFAXALONEDEXMEDETOMIDINE-FOR-SEDATION-IN/10.1638/2023-0013.full |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 9–15 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 6-9 mg/kg IV, or 9-15 mg/kg IM182 Most species/good muscle relaxation; variable results; drug requires more evaluation; may have violent recovery;198don’t use within 10 days of DMS |
| 3 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 3 mg/kg IV252 Crocodilians/induction, but unpredictable results |
| 5–25 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.4 | 5-25 mg/kg IM (Lennox, Proc ARAV, 2013, pp 66-68) Most species/recommend starting at lower dose (5-10 mg/kg) and titrating up |
| 6–9 | IV | Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed |
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These ranges are per kg. Enter your houston toad's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Neuroactive steroid that modulates GABA-A receptors, producing dose-dependent sedation to general anesthesia.
Apnea with rapid IV injection — titrate slowly. No analgesic properties. Short shelf life once broached (use within 6 hours unless preserved formulation). Good safety profile in exotic species.
Species-specific contraindications and adverse-reaction reports for houston toads may differ from canine / feline reference data — consult the primary citations listed with each rule.
Alfaxalone dose range in houston toads, with cited source references: SC 12 mg/kg Single dose per sedation episode. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Alfaxalone in houston toads: SC.
Alfaxalone is indicated in houston toads for: Sedation for handling, examination and minor procedures.
These are general warnings for Alfaxalone across species; consult the houston toad dosing table above for species-specific guidance. Apnea with rapid IV injection — titrate slowly. No analgesic properties. Short shelf life once broached (use within 6 hours unless preserved formulation). Good safety profile in exotic species.
Why a species-specific page? Alfaxalone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in houston toads — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 6-9 mg/kg IV, or 9-15 mg/kg IM182 Most species/good muscle relaxation; variable results; drug requires more evaluation; may have violent recovery;198don’t use within 10 days of DMS |
| 6–15 | IM | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 127.4 | 6-15 mg/kg IM, IV298 Most species |
| Dose (mg/l) | Route | Source | As printed |
|---|---|---|---|
| 200 | IN | Carpenter's Exotic Animal Formulary, 6th edTable 3.4 | 200 mg/L in fresh water buffered bath |
| 200 | — | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.4 | 200 mg/L in fresh water bath2 Fire-bellied toads/buffer with sodium bicarbonate to pH 7.2; anesthetic induction in 14 ± 4 min, variable duration of anesthesia up to 30 min; not suf |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.