Auranofin for Gerbils
Pocket Pet · Meriones unguiculatus · typical adult weight 0.07–0.13 kg
Auranofin is dosed at 5 mg/kg PO BID weekdays and SID weekends for a total of 48… in gerbils, per Repurposing Auranofin as a Lead Candidate for Treatment of Lymphatic Filariasis and Onchocerciasis. PLoS Neglected Tropical Diseases (PLoS Negl Trop Dis). 2015. DOI: 10.1371/journal.pntd.0003534. URL: https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0003534. Auranofin is used in gerbils for Brugia pahangi infection (lymphatic filariasis model). Routes documented in gerbils: PO. A typical adult gerbil weighs 0.07–0.13 kg. ExoticRx lists 1 cited dose rule for Auranofin in gerbils, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Ridaura
Dose ranges
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 5 mg/kg | BID weekdays and SID weekends for a total of 48… | Brugia pahangi infection (lymphatic filariasis model) | Weak | Repurposing Auranofin as a Lead Candidate for Treatment of Lymphatic Filariasis and Onchocerciasis. PLoS Neglected Tropical Diseases (PLoS Negl Trop Dis). 2015. DOI: 10.1371/journal.pntd.0003534. URL: https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0003534 |
Need the exact dose for your patient?
These ranges are per kg. Enter your gerbil's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Oral gold salt with immunomodulatory and anti-inflammatory properties. Inhibits macrophage and lymphocyte function. Mechanism not fully understood.
Side effects & warnings
Used for immune-mediated skin diseases (pemphigus). Slow onset (weeks to months). Toxicity: diarrhea, proteinuria, bone marrow suppression. Monitor CBC and urinalysis. Largely replaced by newer agents.
Species-specific contraindications and adverse-reaction reports for gerbils may differ from canine / feline reference data — consult the primary citations listed with each rule.
Frequently asked questions
What is the dose of Auranofin for Gerbils?
Auranofin dose range in gerbils, with cited source references: PO 5 mg/kg BID weekdays and SID weekends for a total of 48….
How is Auranofin administered in Gerbils?
Documented routes for Auranofin in gerbils: PO.
What conditions does Auranofin treat in Gerbils?
Auranofin is indicated in gerbils for: Brugia pahangi infection (lymphatic filariasis model).
What are the side effects of Auranofin in Gerbils?
These are general warnings for Auranofin across species; consult the gerbil dosing table above for species-specific guidance. Used for immune-mediated skin diseases (pemphigus). Slow onset (weeks to months). Toxicity: diarrhea, proteinuria, bone marrow suppression. Monitor CBC and urinalysis. Largely replaced by newer agents.
Auranofin dosing in other species
Why a species-specific page? Auranofin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in gerbils — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.