Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Buprenorphine extended-release is dosed at 3.25 mg/kg SC once in mice, per ETHIQA XR - Buprenorphine Hydrochloride Injection, Suspension, Extended Release [US Product Label]. New Brunswick, NJ: Fidelis Pharmaceuticals; 2021. — Plumb's 10th ed printed p.150, Buprenorphine monograph spanning p.150-154. Buprenorphine extended-release is used in mice for post-operative analgesia (incisional pain model). Routes documented in mice: SC. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 2 cited dose rules for Buprenorphine extended-release in mice, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| SC | 3.25 mg/kg | once | post-operative analgesia (incisional pain model) | Weak | ETHIQA XR - Buprenorphine Hydrochloride Injection, Suspension, Extended Release [US Product Label]. New Brunswick, NJ: Fidelis Pharmaceuticals; 2021. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6205ff58-853f-4987-b099-c1e263385fc8 — Plumb's 10th ed printed p.150, Buprenorphine monograph spanning p.150-154. |
| SC | 6.5 mg/kg | once | post-operative analgesia (incisional pain model) | Weak | Navarro KL, et al. Lipid bound extended release buprenorphine (high and low doses) and sustained release buprenorphine effectively attenuate post-operative hypersensitivity in an incisional pain model in mice (Mus musculus). Animal Models and Experimental Medicine. 2021. DOI 10.1002/ame2.12157; PMID 34179720; PMCID PMC8212827. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC8212827/ |
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Buprenorphine extended-release dose ranges in mice, with cited source references: SC 3.25 mg/kg once; SC 6.5 mg/kg once. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Buprenorphine extended-release in mice: SC.
Buprenorphine extended-release is indicated in mice for: post-operative analgesia (incisional pain model).
Why a species-specific page? Buprenorphine extended-release pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mice — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.