Question 1

What routes can Buserelin be administered by?

Accepted Answer

Available routes: IM.

Question 2

Which species have cited Buserelin dosing data?

Accepted Answer

Buserelin dosing in the ExoticRx formulary covers 3 species: Betta (Siamese fighting fish), Goldfish, Koi.

Question 3

Is Buserelin a controlled substance?

Accepted Answer

Buserelin is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Question 4

What are the warnings or contraindications for Buserelin?

Accepted Answer

ADVERSE REACTIONS (BSAVA Part B p.59, verbatim): Anaphylactic reactions may occasionally occur.

SAFETY AND HANDLING (BSAVA Part B p.59, verbatim): Pregnant women should not administer the product.

ACTION (BSAVA Part B p.59, verbatim): Synthetic GnRH (gonadotrophin releasing hormone) analogue that stimulates LH and FSH production, thus causing oestrus to develop and progress.

USE (BSAVA Part B p.59, verbatim): To supplement natural LH in cases of ovulation failure or delay. Will also induce lactation postpartum in mammals. In males, it may stimulate testosterone secretion and is indicated in the management of genital hypoplasia and reduced libido. In ferrets it may be used in the management of signs of oestrus. In rabbits it is used to induce ovulation postpartum for insemination and to improve conception rates. In guinea pigs it can be used to resolve ovarian cysts if hormone-responsive. Used in birds for chronic egg laying (must be combined with husbandry changes). Used in trout to facilitate stripping in both male and female fish in spawning condition, and reduce mortality due to egg binding.

SOURCE: Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.59.

Question 5

What are the side effects of Buserelin?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Buserelin: ADVERSE REACTIONS (BSAVA Part B p.59, verbatim): Anaphylactic reactions may occasionally occur.

SAFETY AND HANDLING (BSAVA Part B p.59, verbatim): Pregnant women should not administer the product.

ACTION (BSAVA Part B p.59, verbatim): Synthetic GnRH (gonadotrophin releasing hormone) analogue that stimulates LH and FSH production, thus causing oestrus to develop and progress.

USE (BSAVA Part B p.59, verbatim): To supplement natural LH in cases of ovulation failure or delay. Will also induce lactation postpartum in mammals. In males, it may stimulate testosterone secretion and is indicated in the management of genital hypoplasia and reduced libido. In ferrets it may be used in the management of signs of oestrus. In rabbits it is used to induce ovulation postpartum for insemination and to improve conception rates. In guinea pigs it can be used to resolve ovarian cysts if hormone-responsive. Used in birds for chronic egg laying (must be combined with husbandry changes). Used in trout to facilitate stripping in both male and female fish in spawning condition, and reduce mortality due to egg binding.

SOURCE: Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.59.

Buserelin

Drug Class

Routes

Side effects & warnings

Species with Buserelin dosing data (3 dose rules)

Evidence levels across 3 dose rules

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