Clindamycin Oral Rinse for Cats

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Clindamycin Oral Rinse is dosed at 5.5–11 mg/kg PO q12h in cats, per ANTIROBE - Clindamycin Hydrochloride Capsules and Oral Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2017. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2224602-6f04-4b83-968a-8c193230998f — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.108 (2026-08-01).. Clindamycin Oral Rinse is used in cats for Dental infections, stomatitis. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Clindamycin Oral Rinse in cats, drawn from published veterinary references. Verify against current literature before clinical use.

US trade names: Antirobe Aquadrops

Contraindicated in Rabbit, Chinchilla, Hamster, Degu, Guinea Pig

Rabbit: Oral lincosamides cause fatal dysbiosis in rabbitsSame mechanism as oral beta-lactams — selective destruction of gram-positive hindgut flora. Never administer oral clindamycin or lincomycin to rabbits.
Chinchilla: Oral lincosamides cause fatal dysbiosis in chinchillasClindamycin and lincomycin destroy gram-positive hindgut flora and precipitate fatal Clostridium enterotoxemia in chinchillas. Never administer.
Hamster: Oral lincosamides cause fatal enterocolitis in hamstersClindamycin and lincomycin are among the antibiotics that induce fatal Clostridium difficile enterocolitis in hamsters. Never administer.
Degu: Oral lincosamides risk fatal dysbiosis in degusExtrapolated from chinchillas and guinea pigs (shared caviomorph hindgut physiology): oral clindamycin/lincomycin should be treated as contraindicated in degus.
Guinea Pig: Oral lincosamides cause fatal dysbiosis in guinea pigsClindamycin and lincomycin cause the same fatal Clostridium enterotoxemia in guinea pigs as oral beta-lactams. Never administer.

Dose ranges

Route	Dose	Frequency	Duration	Indication	Evidence	Source
PO	5.5–11 mg/kg	q12h	10-28 days	Dental infections, stomatitis	Strong	ANTIROBE - Clindamycin Hydrochloride Capsules and Oral Solution [US Product Label for Dogs and Cats]. Zoetis Inc.; 2017. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2224602-6f04-4b83-968a-8c193230998f — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.108 (2026-08-01).

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Mechanism of action

Lincosamide antibiotic with excellent bone and dental tissue penetration. Inhibits bacterial protein synthesis at 50S ribosomal subunit.

Side effects & warnings

GI upset possible. Concentrates in bone, making it ideal for dental/osteomyelitis infections. Avoid in rabbits and rodents (fatal enterocolitis).

Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.

Frequently asked questions

What is the dose of Clindamycin Oral Rinse for Cats?

Clindamycin Oral Rinse dose range in cats, with cited source references: PO 5.5–11 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.

How is Clindamycin Oral Rinse administered in Cats?

Documented routes for Clindamycin Oral Rinse in cats: PO.

How long is Clindamycin Oral Rinse given in Cats?

Cited course lengths for Clindamycin Oral Rinse in cats include: 10-28 days. Duration depends on the indication — match it to the specific dose rule in the table above.

What conditions does Clindamycin Oral Rinse treat in Cats?

Clindamycin Oral Rinse is indicated in cats for: Dental infections, stomatitis.

What are the side effects of Clindamycin Oral Rinse in Cats?

These are general warnings for Clindamycin Oral Rinse across species; consult the cat dosing table above for species-specific guidance. GI upset possible. Concentrates in bone, making it ideal for dental/osteomyelitis infections. Avoid in rabbits and rodents (fatal enterocolitis).

Clindamycin Oral Rinse dosing in other species

Dogs

See all species for Clindamycin Oral Rinse See all drugs for Cats

Why a species-specific page? Clindamycin Oral Rinse pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.