Livestock · Sus scrofa domesticus · typical adult weight 1.00–300.00 kg
Fenbendazole is dosed at 3 mg/kg PO q24h x 3 days (9 mg/kg total course) in swine, per 21 CFR 558.258(e)(2)(i), Swine — "Feed as the sole ration to provide 9 mg/kg of body weight (4.08 mg/lb) over a period of 3 to 12 […]" https://www.ecfr.gov/current/title-21/chapter-I/subchapter-E/part-558/subpart-B/section-558.258 — DAILY RATE: FDA Freedom of Information Summary, NADA 131-675, §IV.1 Suidae — "a treatment regimen of 3 mg/kg bw daily for 3 days". https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/398 — PRODUCT LABEL: SAFE-GUARD (fenbendazole), NADA 131-675, Merck Animal Health, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e1bb5aa8-3316-47f1-be79-cdbcd62b7222 — NOTE: the label's 5 mg/kg figure is the CATTLE free-choice rate and does not apply to swine.. Fenbendazole is used in swine for GI nematodes, lungworms. Routes documented in swine: PO. A typical adult swine weighs 1.00–300.00 kg. ExoticRx lists 1 cited dose rule for Fenbendazole in swine, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Panacur
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 3 mg/kg | q24h x 3 days (9 mg/kg total course) | 3 days at 3 mg/kg/day = the labelled 9 mg/kg total; the label permits the same total spread over 3-12 consecutive days. Meat withdrawal 4 days. | GI nematodes, lungworms | Weak | 21 CFR 558.258(e)(2)(i), Swine — "Feed as the sole ration to provide 9 mg/kg of body weight (4.08 mg/lb) over a period of 3 to 12 […]" https://www.ecfr.gov/current/title-21/chapter-I/subchapter-E/part-558/subpart-B/section-558.258 — DAILY RATE: FDA Freedom of Information Summary, NADA 131-675, §IV.1 Suidae — "a treatment regimen of 3 mg/kg bw daily for 3 days". https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/398 — PRODUCT LABEL: SAFE-GUARD (fenbendazole), NADA 131-675, Merck Animal Health, https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e1bb5aa8-3316-47f1-be79-cdbcd62b7222 — NOTE: the label's 5 mg/kg figure is the CATTLE free-choice rate and does not apply to swine. |
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Binds to beta-tubulin, inhibiting microtubule polymerization in parasites. Disrupts energy metabolism and cell division.
Very wide safety margin. Rarely causes vomiting or diarrhea. Safe in pregnant animals at standard doses. Must be given for multiple consecutive days for efficacy.
Species-specific contraindications and adverse-reaction reports for swine may differ from canine / feline reference data — consult the primary citations listed with each rule.
Fenbendazole dose range in swine, with cited source references: PO 3 mg/kg q24h x 3 days (9 mg/kg total course). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Fenbendazole in swine: PO.
Cited course lengths for Fenbendazole in swine include: 3 days at 3 mg/kg/day = the labelled 9 mg/kg total; the label permits the same total spread over 3-12 consecutive days. Meat withdrawal 4 days.. Duration depends on the indication — match it to the specific dose rule in the table above.
Fenbendazole is indicated in swine for: GI nematodes, lungworms.
These are general warnings for Fenbendazole across species; consult the swine dosing table above for species-specific guidance. Very wide safety margin. Rarely causes vomiting or diarrhea. Safe in pregnant animals at standard doses. Must be given for multiple consecutive days for efficacy.
Why a species-specific page? Fenbendazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in swine — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.