Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Gabapentin is dosed at 3–5 mg/kg PO q12-24h in guinea pigs, per Quesenberry KE, Orcutt CJ, Mans C, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, Appendix: Formulary (Morrisey JK, Carpenter JW), Table A.4, p.638, column 'Guinea Pigs/Chinchillas' — 'Gabapentin 3-5 mg/kg PO q12-24h'. Corroborated by Exotic Animal Emergency and Critical Care Medicine, Table 16.1 (Analgesic agents commonly used in guinea pigs), p.301 — 'Gabapentin 3-5 mg/kg PO q12-24h' (Source: Carpenter [11]). — LOCATOR CONVENTION 2026-08-07: the bare 'p.638' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.626; verified by finding the drug named there. If you are holding the book, turn to p.626. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350; Exotic Animal Emergency and Critical Care Medicine — ISBN 9781119149231, https://openlibrary.org/isbn/9781119149231. Gabapentin is used in guinea pigs for Neuropathic pain. Routes documented in guinea pigs: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Gabapentin in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Neurontin
| Route | Dose | Frequency | Duration |
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| Indication |
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| Evidence |
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| Source |
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| PO | 3–5 mg/kg | q12-24h | Chronic use | Neuropathic pain | Extrapolated | Quesenberry KE, Orcutt CJ, Mans C, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, Appendix: Formulary (Morrisey JK, Carpenter JW), Table A.4, p.638, column 'Guinea Pigs/Chinchillas' — 'Gabapentin 3-5 mg/kg PO q12-24h'. Corroborated by Exotic Animal Emergency and Critical Care Medicine, Table 16.1 (Analgesic agents commonly used in guinea pigs), p.301 — 'Gabapentin 3-5 mg/kg PO q12-24h' (Source: Carpenter [11]). — LOCATOR CONVENTION 2026-08-07: the bare 'p.638' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.626; verified by finding the drug named there. If you are holding the book, turn to p.626. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350; Exotic Animal Emergency and Critical Care Medicine — ISBN 9781119149231, https://openlibrary.org/isbn/9781119149231 |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds to alpha-2-delta subunit of voltage-gated calcium channels, modulating neurotransmitter release. Reduces central sensitization.
Sedation common, especially initially. Some oral solutions contain xylitol (toxic to dogs). Taper to discontinue (do not stop abruptly). Adjust dose in renal impairment.
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Gabapentin dose range in guinea pigs, with cited source references: PO 3–5 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Gabapentin in guinea pigs: PO.
Cited course lengths for Gabapentin in guinea pigs include: Chronic use. Duration depends on the indication — match it to the specific dose rule in the table above.
Gabapentin is indicated in guinea pigs for: Neuropathic pain.
These are general warnings for Gabapentin across species; consult the guinea pig dosing table above for species-specific guidance. Sedation common, especially initially. Some oral solutions contain xylitol (toxic to dogs). Taper to discontinue (do not stop abruptly). Adjust dose in renal impairment.
Why a species-specific page? Gabapentin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.