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Gabapentin for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Gabapentin is used in guinea pig for Neuropathic pain. Routes documented in guinea pig: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Gabapentin in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Neurontin

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO5–15 mg/kgq8-12hChronic useNeuropathic painExtrapolatedCarpenter's Exotic Animal Formulary, 6th Ed

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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Binds to alpha-2-delta subunit of voltage-gated calcium channels, modulating neurotransmitter release. Reduces central sensitization.

Side effects & warnings

Sedation common, especially initially. Some oral solutions contain xylitol (toxic to dogs). Taper to discontinue (do not stop abruptly). Adjust dose in renal impairment.

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Analgesic drugs with guinea pig dosing

Gabapentin dosing in other species

Why a species-specific page? Gabapentin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.