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Prednisolone for Cattle

Livestock · Bos taurus · typical adult weight 250.00–900.00 kg

Prednisolone is used in cattle for Inflammation, allergic reactions. Routes documented in cattle: IM. A typical adult cattle weighs 250.00–900.00 kg. ExoticRx lists 1 cited dose rule for Prednisolone in cattle, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Delta-Cortef, Prelone

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IM0.5–1 mg/kgq24h3-5 daysInflammation, allergic reactionsModeratePlumb's Veterinary Drug Handbook, 9th Ed

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These ranges are per kg. Enter your cattle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Binds intracellular glucocorticoid receptors, modulating gene transcription. Suppresses inflammatory and immune responses at multiple levels.

Side effects & warnings

PU/PD, polyphagia, weight gain, iatrogenic Cushing's. Immunosuppression risk. GI ulceration (especially with NSAIDs). Do not abruptly discontinue after chronic use. Cats require prednisolone (not prednisone).

Species-specific contraindications and adverse-reaction reports for cattle may differ from canine / feline reference data — consult the primary citations listed with each rule.

Prednisolone dosing in other species

Why a species-specific page? Prednisolone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cattle — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.