Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg
Prednisolone is dosed at 10–20 mg/kg IM, IV, IP once in guinea pigs, per Ewringmann A, Gloeckner B. Leitsymptome bei Meerschweinchen, Chinchilla und Degu, Enke, Stuttgart, Germany; 2012. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.797 (2026-08-01, PENDING REVIEW). Prednisolone is used in guinea pigs for Shock, Anti-inflammatory (glucocorticoid). Routes documented in guinea pigs: IM, IV, IP, PO, SC. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 2 cited dose rules for Prednisolone in guinea pigs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Delta-Cortef, Prelone
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM, IV, IP | 10–20 mg/kg | once | Shock | Weak | Ewringmann A, Gloeckner B. Leitsymptome bei Meerschweinchen, Chinchilla und Degu, Enke, Stuttgart, Germany; 2012. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.797 (2026-08-01, PENDING REVIEW) |
| PO, SC | 1–2 mg/kg | q12-24h | Anti-inflammatory (glucocorticoid) | Moderate | Ewringmann A, Gloeckner B. Leitsymptome bei Meerschweinchen, Chinchilla und Degu, Enke, Stuttgart, Germany; 2012. / Fehr M, Sassenburg L, Zwart P. Krankheiten der Heimtiere, 8th ed., Schluetersche Verlagsgesellschaft, Hannover, Germany; 2015. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.802 (2026-08-01, PENDING REVIEW) doi:10.1055/b-004-129947 |
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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds intracellular glucocorticoid receptors, modulating gene transcription. Suppresses inflammatory and immune responses at multiple levels.
PU/PD, polyphagia, weight gain, iatrogenic Cushing's. Immunosuppression risk. GI ulceration (especially with NSAIDs). Do not abruptly discontinue after chronic use. Cats require prednisolone (not prednisone).
Species-specific contraindications and adverse-reaction reports for guinea pigs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Prednisolone dose ranges in guinea pigs, with cited source references: IM, IV, IP 10–20 mg/kg once; PO, SC 1–2 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Prednisolone in guinea pigs: IM, IV, IP, PO, SC.
Prednisolone is indicated in guinea pigs for: Shock, Anti-inflammatory (glucocorticoid).
These are general warnings for Prednisolone across species; consult the guinea pig dosing table above for species-specific guidance. PU/PD, polyphagia, weight gain, iatrogenic Cushing's. Immunosuppression risk. GI ulceration (especially with NSAIDs). Do not abruptly discontinue after chronic use. Cats require prednisolone (not prednisone).
Why a species-specific page? Prednisolone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pigs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.