Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Valacyclovir is dosed at 40 mg/kg PO q24h in eastern box turtles, per 4. Allender MC, Mitchell MA, Yarborough J, et al. Pharmocokinetics of a single oral dose of acyclovir and valacyclovir in North American box turtles (Terrapene sp.). J Vet Pharmacol Therap. 2012;36:205-208. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530. Valacyclovir is used in eastern box turtles for herpesvirus. Routes documented in eastern box turtles: PO. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 1 cited dose rule for Valacyclovir in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Valtrex
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 40 mg/kg | q24h | herpesvirus | Weak | 4. Allender MC, Mitchell MA, Yarborough J, et al. Pharmocokinetics of a single oral dose of acyclovir and valacyclovir in North American box turtles (Terrapene sp.). J Vet Pharmacol Therap. 2012;36:205-208. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 40 | PO | Carpenter's Exotic Animal Formulary, 6th edTable 4.2 | 40 mg/kg PO q24h |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Prodrug rapidly converted to acyclovir. Triphosphorylated form inhibits viral DNA polymerase and causes chain termination. Active against herpesviruses.
TOXIC TO CATS — causes acute hepatic necrosis and fatal bone marrow suppression. Dogs tolerate well. Ensure adequate hydration.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Valacyclovir dose range in eastern box turtles, with cited source references: PO 40 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Valacyclovir in eastern box turtles: PO.
Valacyclovir is indicated in eastern box turtles for: herpesvirus.
These are general warnings for Valacyclovir across species; consult the eastern box turtle dosing table above for species-specific guidance. TOXIC TO CATS — causes acute hepatic necrosis and fatal bone marrow suppression. Dogs tolerate well. Ensure adequate hydration.
Why a species-specific page? Valacyclovir pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.