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Bacterial Infections in Bearded Dragons

Reptile · Pogona vitticeps · typical adult weight 0.38–0.51 kg

11 cited drugs treat Bacterial Infections in bearded dragons: Amoxicillin, Ampicillin, Cefotaxime, Ceftazidime, Ceftiofur, Chloramphenicol, Enrofloxacin, Enrofloxacin Injectable, Oxytetracycline, Trimethoprim-Sulfamethoxazole, Vitamin C (Ascorbic Acid).

General coverage of susceptible bacterial pathogens. Drug selection turns on the suspected organism's gram-stain, the patient's species (oral β-lactams unsafe in rabbits/guinea pigs), and the infection site (penetration to bone, CSF, or biliary tree).

The overview above describes Bacterial Infections across species; the citations below are the ExoticRx dose rules scoped to bearded dragons — a reference list, not new species-specific clinical guidance.

Amoxicillin(Amoxi-Tabs, Amoxil)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO10–22 mg/kgq12-24h7-14 daysSusceptible bacterial infectionsExtrapolatedDivers SJ. Empirical doses of antimicrobial drugs commonly used in reptiles. Exot DVM. 1998;1:23.; Hedley J. BSAVA Small Animal Formulary: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, UK; 2020. — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).Compilation only — we have not located an independent source that prints this figure.

Ampicillin(Polyflex)

Antibiotic
RouteDoseFrequencyIndicationEvidenceSource
SC, IM10–20 mg/kgq12hBacterial infection (may be used with an aminoglycoside)Weak184. Hedley J. BSAVA Small Animal Formulary: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, UK; 2020. / 243. Klaphake E, Gibbons PM, Sladky KK, et al. Reptiles. In: Carpenter JW, eds. Exotic Animal Formulary, 5th ed., Elsevier, St. Louis, MO; 2018:81-166. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.212 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).Compilation only — we have not located an independent source that prints this figure.

Cefotaxime(Claforan)

Antibiotic
RouteDoseFrequencyIndicationEvidenceSource
IM20–40 mg/kgq24hBacterial infection (may use with an aminoglycoside)Weak243. Klaphake E, Gibbons PM, Sladky KK, et al. Reptiles. In: Carpenter JW, eds. Exotic Animal Formulary, 5th ed., Elsevier, St. Louis, MO; 2018:81-166. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.213 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).Compilation only — we have not located an independent source that prints this figure.

Ceftazidime(Fortaz)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
IM20 mg/kgq48-72h—Gram-negative bacterial infectionsModerateWhite SD, Bourdeau P, Bruet V, et al. Reptiles with dermatological lesions: a retrospective study of 301 cases at two university veterinary teaching hospitals (1992-2008). Vet Dermatol. 2010;22:150-161. doi:10.1111/j.1365-3164.2010.00926.x; Funk RS. A formulary for lizards, snakes, and crocodilians. Vet Clin North Am Exot Anim Pract. 2000;3:333-358. doi:10.1016/s1094-9194(17)30105-6 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).
SC20 mg/kgq72h14-21 daysGram-negative bacterial infectionsModerateFunk RS. A formulary for lizards, snakes, and crocodilians. Vet Clin North Am Exot Anim Pract. 2000;3:333-358. doi:10.1016/s1094-9194(17)30105-6; Stahl SJ. Pet lizard conditions and syndromes. Semin Avian Exot Pet Med. 2003;12:162-182. doi:10.1053/saep.2003.00019-7 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).

Ceftiofur(Excenel, Excede, Naxcel)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
IM5 mg/kgq24h7-14 daysBacterial infectionsWeakCarpenter's 6th ed. p.214 (ceftiofur sodium, lizards/bearded dragons); Mader's Table 127.1 '5 mg/kg SC, IM q24h - Lizards/PK; ceftiofur sodium'; Plumb's Ceftiofur REPTILES, '5 mg/kg, IM or SC, every 24 hours' (green iguana PK) https://doi.org/10.1016/j.vetmic.2009.05.003 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).Compilation only — we have not located an independent source that prints this figure.

Chloramphenicol

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO40 mg/kgq24h7-14 daysBacterial infectionsExtrapolatedCarpenter's Exotic Animal Formulary, 6th Ed, Table 4.1 antimicrobials continuation, Chloramphenicol, 'Most species' row; superscript 142 = Funk RS. A formulary for lizards, snakes, and crocodilians. Vet Clin North Am Exot Anim Pract. 2000;3:333-358 10.1016/s1094-9194(17)30105-6Compilation only — we have not located an independent source that prints this figure.

Enrofloxacin(Baytril)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
IM5–10 mg/kgq24h7-14 daysBacterial infectionsModerateCarpenter's Exotic Animal Formulary, 6th ed, pp.215-216 (Enrofloxacin, reptiles). Primaries printed in the chapter reference list: ref 409 = Salvadori M, Vercelli C, De Vito V, et al. Pharmacokinetic and pharmacodynamic evaluations of a 10 mg/kg enrofloxacin intramuscular administration in bearded dragons (Pogona vitticeps) [Carpenter refs p.391]; ref 188 = Hellebuyck T, Pasmans F, Haesebrouck F, et al. Designing a successful antimicrobial treatment against Devriesea agamarum infections in lizards. Vet Microbiol. 2009;139:189-192 [Carpenter refs p.364] — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).Compilation only — we have not located an independent source that prints this figure.
IM5–10 mg/kgq24h7-14 daysBacterial infectionsModerateSalvadori M, Vercelli C, De Vito V, et al. Pharmacokinetic and pharmacodynamic evaluations of a 10 mg/kg enrofloxacin intramuscular administration in bearded dragons (Pogona vitticeps): a preliminary assessment. J Vet Pharm Ther. 2017;40:62-69. doi:10.1111/jvp.12320; Hellebuyck T, Pasmans F, Haesebrouck F, et al. Designing a successful antimicrobial treatment against Devriesea agamarum infections in lizards. Vet Microbiol. 2009;139:189-192. doi:10.1016/j.vetmic.2009.05.003 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).
PO5–10 mg/kgq24h7-14 daysBacterial infectionsExtrapolatedAgius JE, Kimble B, Govendir M, et al. Pharmacokinetic profile of enrofloxacin and its metabolite ciprofloxacin in Asian house geckos (Hemidactylus frenatus) after single-dose oral administration of enrofloxacin. Vet Anim Sci; 2020:100-116. doi:10.1016/j.vas.2020.100116 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).

Enrofloxacin Injectable(Baytril Injectable)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
IM5–10 mg/kgq24h7-14 daysBacterial infectionsModerateSalvadori M, Vercelli C, De Vito V, et al. Pharmacokinetic and pharmacodynamic evaluations of a 10 mg/kg enrofloxacin intramuscular administration in bearded dragons (Pogona vitticeps): a preliminary assessment. J Vet Pharm Ther. 2017;40:62-69. doi:10.1111/jvp.12320 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).

Oxytetracycline(Terramycin, Liquamycin)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
PO, IM, IV6–10 mg/kgq24h14-21 daysBacterial infectionsExtrapolatedCarpenter's Exotic Animal Formulary 6th ed., Antimicrobial Agents Used in Reptiles, p.218; refs 107 + 243 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).Compilation only — we have not located an independent source that prints this figure.

Trimethoprim-Sulfamethoxazole(Bactrim, TMS)

Antibiotic
RouteDoseFrequencyDurationIndicationEvidenceSource
IM15–25 mg/kg/dayq24h for 7 to 14 days7-14 daysBacterial infectionsExtrapolatedPlumb's Veterinary Drug Handbook, 10th ed (2023), Sulfa-/Trimethoprim monograph, REPTILES section entry c), printed p.1196, superscript 46 → Lewbart. Reptile formulary. Presented at: Atlantic Coast Veterinary Conference; 2001Compilation only — we have not located an independent source that prints this figure.
PO15–25 mg/kgq24h—Bacterial infections, coccidiaExtrapolatedGibbons PM, Klaphake E, Carpenter JW. Reptiles. In: Carpenter JW, ed. Exotic Animal Formulary. 4th ed. St. Louis: Elsevier; 2013:83-182. — Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1404Compilation only — we have not located an independent source that prints this figure.
RouteDoseFrequencyDurationIndicationEvidenceSource
SC, IM10–20 mg/kgq24hShort-term during illnessHypovitaminosis C, stomatitis, skin slough (snakes), supportive therapy for bacterial infectionsAnecdotalCarpenter's Exotic Animal Formulary, 6th ed., Table 4.10 (vitamins/nutritional support, reptiles), p.268, Vitamin C row, superscript 138 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.9 (Nutritional/Mineral/Fluid Support Used in Reptiles.a).Compilation only — we have not located an independent source that prints this figure.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice. Verify against current literature before clinical use.