Cat · Felis catus · typical adult weight 2.50–7.00 kg
Acepromazine is dosed at 0.05–0.1 mg/kg IM Single dose in cats, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01).. Acepromazine is used in cats for Pre-anesthetic sedation. Routes documented in cats: IM. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Acepromazine in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: PromAce, Atravet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0.05–0.1 mg/kgmax 1 mg total | Single dose | Pre-anesthetic | Pre-anesthetic sedation | Strong | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01). |
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Blocks dopamine D2 receptors in the CNS, producing sedation and anxiolysis. Also has alpha-1 adrenergic blocking properties causing vasodilation.
Hypotension (alpha blockade) — avoid in hypovolemic patients. DO NOT use in giant breeds (boxers extremely sensitive — exaggerated hypotension). No analgesic effect. Lowers seizure threshold. Not reversible.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Acepromazine dose range in cats, with cited source references: IM 0.05–0.1 mg/kg Single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Acepromazine in cats: IM.
Cited course lengths for Acepromazine in cats include: Pre-anesthetic. Duration depends on the indication — match it to the specific dose rule in the table above.
Acepromazine is indicated in cats for: Pre-anesthetic sedation.
These are general warnings for Acepromazine across species; consult the cat dosing table above for species-specific guidance. Hypotension (alpha blockade) — avoid in hypovolemic patients. DO NOT use in giant breeds (boxers extremely sensitive — exaggerated hypotension). No analgesic effect. Lowers seizure threshold. Not reversible.
Why a species-specific page? Acepromazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.