Cat · Felis catus · typical adult weight 2.50–7.00 kg
Acepromazine is dosed at 0.05–0.1 mg/kg IM Single dose in cats, per Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.33 (2026-08-01). — Plumb's 10th ed (held) printed p.2, Acepromazine monograph spanning p.2-6; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Acepromazine is used in cats for Pre-anesthetic sedation. Routes documented in cats: IM. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Acepromazine in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: PromAce, Atravet
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 0.05–0.1 mg/kg | Single dose | Pre-anesthetic | Pre-anesthetic sedation | Strong |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.025–0.1 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.30 | • 0.025-0.1 mg/kg IM, IV, or SQ in a • 0.025-0.1 mg/kg IM, IV, or SQ in a |
| 1.1–2.2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.30 | mg/kg). Do not exceed 3 mg total in • Sedation: 1.1-2.2 mg/kg q6-8h PO. |
| 0.5–2.2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.30 | • Sedation: 0.5-2.2 mg/kg q6-8h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Blocks dopamine D2 receptors in the CNS, producing sedation and anxiolysis. Also has alpha-1 adrenergic blocking properties causing vasodilation.
Hypotension (alpha blockade) — avoid in hypovolemic patients. DO NOT use in giant breeds (boxers extremely sensitive — exaggerated hypotension). No analgesic effect. Lowers seizure threshold. Not reversible.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Acepromazine dose range in cats, with cited source references: IM 0.05–0.1 mg/kg Single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Acepromazine in cats: IM.
Cited course lengths for Acepromazine in cats include: Pre-anesthetic. Duration depends on the indication — match it to the specific dose rule in the table above.
Acepromazine is indicated in cats for: Pre-anesthetic sedation.
These are general warnings for Acepromazine across species; consult the cat dosing table above for species-specific guidance. Hypotension (alpha blockade) — avoid in hypovolemic patients. DO NOT use in giant breeds (boxers extremely sensitive — exaggerated hypotension). No analgesic effect. Lowers seizure threshold. Not reversible.
Why a species-specific page? Acepromazine pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.