Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Alfaxalone is dosed at 80 mg/kg IP once (induction) in mice, per 158. Siriarchavatana P, Ayers JD, Kendall LV. Anesthetic activity of alfaxalone compared with ketamine in mice. J Am Assoc Lab Anim Sci. 2016;55:426-430. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.782 (2026-08-01, PENDING REVIEW) PMID: 27423149. Alfaxalone is used in mice for Surgical anesthesia. Routes documented in mice: IP. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 1 cited dose rule for Alfaxalone in mice, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Alfaxan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IP | 80 mg/kg | once (induction) | Surgical anesthesia | Moderate | 158. Siriarchavatana P, Ayers JD, Kendall LV. Anesthetic activity of alfaxalone compared with ketamine in mice. J Am Assoc Lab Anim Sci. 2016;55:426-430. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.782 (2026-08-01, PENDING REVIEW) PMID: 27423149 |
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Neuroactive steroid that modulates GABA-A receptors, producing dose-dependent sedation to general anesthesia.
Apnea with rapid IV injection — titrate slowly. No analgesic properties. Short shelf life once broached (use within 6 hours unless preserved formulation). Good safety profile in exotic species.
Species-specific contraindications and adverse-reaction reports for mice may differ from canine / feline reference data — consult the primary citations listed with each rule.
Alfaxalone dose range in mice, with cited source references: IP 80 mg/kg once (induction). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Alfaxalone in mice: IP.
Alfaxalone is indicated in mice for: Surgical anesthesia.
These are general warnings for Alfaxalone across species; consult the mouse dosing table above for species-specific guidance. Apnea with rapid IV injection — titrate slowly. No analgesic properties. Short shelf life once broached (use within 6 hours unless preserved formulation). Good safety profile in exotic species.
Why a species-specific page? Alfaxalone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mice — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.