Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Alfaxalone is dosed at 80 mg/kg IP once (induction) in mice, per 158. Siriarchavatana P, Ayers JD, Kendall LV. Anesthetic activity of alfaxalone compared with ketamine in mice. J Am Assoc Lab Anim Sci. 2016;55:426-430. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.782 PMID: 27423149 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.3 (Chemical Restraint/Anesthetic Agents Used in Rodents). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Alfaxalone is used in mice for Surgical anesthesia. Routes documented in mice: IP. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 1 cited dose rule for Alfaxalone in mice, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Alfaxan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IP | 80 mg/kg | once (induction) | Surgical anesthesia | Moderate | 158. Siriarchavatana P, Ayers JD, Kendall LV. Anesthetic activity of alfaxalone compared with ketamine in mice. J Am Assoc Lab Anim Sci. 2016;55:426-430. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.782 PMID: 27423149 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.3 (Chemical Restraint/Anesthetic Agents Used in Rodents). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 80 | IP | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 80 mg/kg IP |
| 100 | IP | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 100 mg/kg IP, SC |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Neuroactive steroid that modulates GABA-A receptors, producing dose-dependent sedation to general anesthesia.
Apnea with rapid IV injection — titrate slowly. No analgesic properties. Short shelf life once broached (use within 6 hours unless preserved formulation). Good safety profile in exotic species.
Species-specific contraindications and adverse-reaction reports for mice may differ from canine / feline reference data — consult the primary citations listed with each rule.
Alfaxalone dose range in mice, with cited source references: IP 80 mg/kg once (induction). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Alfaxalone in mice: IP.
Alfaxalone is indicated in mice for: Surgical anesthesia.
These are general warnings for Alfaxalone across species; consult the mouse dosing table above for species-specific guidance. Apnea with rapid IV injection — titrate slowly. No analgesic properties. Short shelf life once broached (use within 6 hours unless preserved formulation). Good safety profile in exotic species.
Why a species-specific page? Alfaxalone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mice — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.