Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Midazolam is dosed at 2–3 mg/kg IM once in mice, per 172. Wenger S. Anesthesia and analgesia in rabbits and rodents. J Exot Pet Med. 2012;21:7-16. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.787 (2026-08-01, PENDING REVIEW) doi:10.1053/j.jepm.2011.11.010. Midazolam is used in mice for Sedation, Preanesthetic sedation. Routes documented in mice: IM. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 2 cited dose rules for Midazolam in mice, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Versed
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 2–3 mg/kg | once | Sedation | Moderate | 172. Wenger S. Anesthesia and analgesia in rabbits and rodents. J Exot Pet Med. 2012;21:7-16. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.787 (2026-08-01, PENDING REVIEW) doi:10.1053/j.jepm.2011.11.010 |
| IM | 1–2 mg/kg | once (preanesthetic) | Preanesthetic sedation | Moderate | 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Mined from Carpenter's Exotic Animal Formulary, 6th Ed, p.787 (2026-08-01, PENDING REVIEW) |
Need the exact dose for your patient?
These ranges are per kg. Enter your mouse's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Enhances GABA-A receptor activity, increasing chloride conductance. Provides anxiolysis, sedation, muscle relaxation, and anticonvulsant effects.
May cause paradoxical excitement in healthy dogs when used alone. Water-soluble (less painful IM than diazepam). Respiratory depression at high doses. Flumazenil is the reversal agent.
Species-specific contraindications and adverse-reaction reports for mice may differ from canine / feline reference data — consult the primary citations listed with each rule.
Midazolam dose ranges in mice, with cited source references: IM 2–3 mg/kg once; IM 1–2 mg/kg once (preanesthetic). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Midazolam in mice: IM.
Midazolam is indicated in mice for: Sedation, Preanesthetic sedation.
These are general warnings for Midazolam across species; consult the mouse dosing table above for species-specific guidance. May cause paradoxical excitement in healthy dogs when used alone. Water-soluble (less painful IM than diazepam). Respiratory depression at high doses. Flumazenil is the reversal agent.
Why a species-specific page? Midazolam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mice — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.