Pocket Pet · Mus musculus · typical adult weight 0.02–0.04 kg
Midazolam is dosed at 2–3 mg/kg IM once in mice, per 172. Wenger S. Anesthesia and analgesia in rabbits and rodents. J Exot Pet Med. 2012;21:7-16. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.787 doi:10.1053/j.jepm.2011.11.010 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.3 (Chemical Restraint/Anesthetic Agents Used in Rodents). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Midazolam is used in mice for Sedation, Preanesthetic sedation. Routes documented in mice: IM, IM, SC. A typical adult mouse weighs 0.02–0.04 kg. ExoticRx lists 2 cited dose rules for Midazolam in mice, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Versed
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 2–3 mg/kg | once | Sedation | Moderate | 172. Wenger S. Anesthesia and analgesia in rabbits and rodents. J Exot Pet Med. 2012;21:7-16. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.787 doi:10.1053/j.jepm.2011.11.010 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.3 (Chemical Restraint/Anesthetic Agents Used in Rodents). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929 |
| IM, SC | 1–2 mg/kg | once (preanesthetic) | Preanesthetic sedation | Moderate | 130. Morrisey JK, Carpenter JW. Formulary. In: Quesenberry KE, Carpenter JW, eds. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.787 — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350 — PRINTED DETAIL MISSING FROM THIS RULE (retrieved 2026-08-19): Same "All species" row covers the mouse, but the next printed row is "2-3 mg/kg IM172 | Rats, mice, gerbils" (Carpenter's Table 9.3), the cited source prints "1.0-2.5 mg/kg SC, IM (R); 1-5 mg/kg SC, IM (M)" (FRR 4e Table A.4, printed p.628), and BSAVA-B prints "Rodents: 2-5 mg/kg i.v., i.m., i.p." (10th ed Part B, printed p.205) — no interval is printed in any of them |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 2–5 | IV | BSAVA Small Animal Formulary, 10th ed — Part B (Exotic Pets)p.219 | 2-5 mg/kg i.v., i.m., i.p. |
| 1–2 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 1-2 mg/kg IM |
| 2–3 | IM | Carpenter's Exotic Animal Formulary, 6th edTable 9.3 | 2-3 mg/kg IM |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Enhances GABA-A receptor activity, increasing chloride conductance. Provides anxiolysis, sedation, muscle relaxation, and anticonvulsant effects.
May cause paradoxical excitement in healthy dogs when used alone. Water-soluble (less painful IM than diazepam). Respiratory depression at high doses. Flumazenil is the reversal agent.
Species-specific contraindications and adverse-reaction reports for mice may differ from canine / feline reference data — consult the primary citations listed with each rule.
Midazolam dose ranges in mice, with cited source references: IM 2–3 mg/kg once; IM, SC 1–2 mg/kg once (preanesthetic). Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Midazolam in mice: IM, IM, SC.
Midazolam is indicated in mice for: Sedation, Preanesthetic sedation.
These are general warnings for Midazolam across species; consult the mouse dosing table above for species-specific guidance. May cause paradoxical excitement in healthy dogs when used alone. Water-soluble (less painful IM than diazepam). Respiratory depression at high doses. Flumazenil is the reversal agent.
Why a species-specific page? Midazolam pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in mice — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.