Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Allopurinol is dosed at 10–20 mg/kg PO q24h in eastern box turtles, per 67. Divers SJ. Medical and surgical treatment of pre-ovulatory ova stasis and post-ovulatory egg stasis in oviparous lizards. Proc Annu Conf Assoc Rept Amph Vet. 1996;119-123. | 217. Mautino M, Page CD. Biology and medicine of turtles and tortoises. Vet Clin North Am Small Anim Pract. 1993;23:1251-1270. | 272. Raiti P. Veterinary care of the common kingsnake, Lampropeltis getula. Bull Assoc Rept Amph Vet. 1995;5:11-18. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 (2026-08-01, PENDING REVIEW). Allopurinol is used in eastern box turtles for gout (decreases production of uric acid), hyperuricaemia/gout. Routes documented in eastern box turtles: PO. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 2 cited dose rules for Allopurinol in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zyloprim, Aloprim
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 10–20 mg/kg | q24h | gout (decreases production of uric acid) | Weak | 67. Divers SJ. Medical and surgical treatment of pre-ovulatory ova stasis and post-ovulatory egg stasis in oviparous lizards. Proc Annu Conf Assoc Rept Amph Vet. 1996;119-123. | 217. Mautino M, Page CD. Biology and medicine of turtles and tortoises. Vet Clin North Am Small Anim Pract. 1993;23:1251-1270. | 272. Raiti P. Veterinary care of the common kingsnake, Lampropeltis getula. Bull Assoc Rept Amph Vet. 1995;5:11-18. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 (2026-08-01, PENDING REVIEW) |
| PO | 50 mg/kg | q24h x 30 days, then q72h | hyperuricaemia/gout | Weak | 171. Koelle P. Efficacy of allopurinol in European tortoises with hyperuricemia. Proc Annu Conf Assoc Rept Amph Vet. 2001;185-186. — Mined from Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1419 (2026-08-01, PENDING REVIEW) |
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These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits xanthine oxidase, reducing conversion of hypoxanthine to xanthine and xanthine to uric acid. Lowers serum and urinary urate levels.
May cause xanthine urolithiasis if protein intake not controlled. Feed low-purine diet concurrently. Monitor uric acid levels and hepatic function.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Allopurinol dose ranges in eastern box turtles, with cited source references: PO 10–20 mg/kg q24h; PO 50 mg/kg q24h x 30 days, then q72h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Allopurinol in eastern box turtles: PO.
Allopurinol is indicated in eastern box turtles for: gout (decreases production of uric acid), hyperuricaemia/gout.
These are general warnings for Allopurinol across species; consult the eastern box turtle dosing table above for species-specific guidance. May cause xanthine urolithiasis if protein intake not controlled. Feed low-purine diet concurrently. Monitor uric acid levels and hepatic function.
Why a species-specific page? Allopurinol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.