ExoticRx · exoticrx.com/drugs/allopurinol
US brand names:Zyloprim, Aloprim
Allopurinol is dosed at 10–20 mg/kg PO q24h in ball pythons, per Raiti P. Veterinary care of the common kingsnake, Lampropeltis getula. Bull Assoc Rept Amph Vet. 1995;5:11-18. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.271 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.11 (Miscellaneous Agents Used in Reptiles). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Inhibits xanthine oxidase, reducing conversion of hypoxanthine to xanthine and xanthine to uric acid. Lowers serum and urinary urate levels.
May cause xanthine urolithiasis if protein intake not controlled. Feed low-purine diet concurrently. Monitor uric acid levels and hepatic function.
Species references:All African Grey Parrot drugsAll Ball Python drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 12 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–15 mg/kg | q12h | Strong | Denerolle P, Bourdoiseau G. Combination allopurinol and antimony treatment versus antimony alone and allopurinol alone in the treatment of canine leishmaniasis (96 cases). J Vet Intern Med. 1999;13(5):413-415. doi:10.1111/j.1939-1676.1999.tb01455.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.65 (2026-08-01). — Plumb's 10th ed (held) printed p.37, Allopurinol monograph spanning p.37-38; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.