ExoticRx · exoticrx.com/drugs/allopurinol
US brand names:Zyloprim, Aloprim
Allopurinol is dosed at 10–20 mg/kg PO q24h in bearded dragons, per Divers SJ. Clinician's approach to renal disease in lizards. Proc Annu Conf Assoc Rept Amph Vet; 1997:5-11.; Mautino M, Page CD. Biology and medicine of turtles and tortoises. Vet Clin North Am Small Anim Pract. 1993;23:1251-1270. PMID: 8249236; Raiti P. Veterinary care of the common kingsnake, Lampropeltis getula. Bull Assoc Rept Amph Vet. 1995;5:11-18. doi:10.5818/1076-3139.5.1.11 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.271 (2026-08-01).. Verify against current literature before clinical use.
Inhibits xanthine oxidase, reducing conversion of hypoxanthine to xanthine and xanthine to uric acid. Lowers serum and urinary urate levels.
May cause xanthine urolithiasis if protein intake not controlled. Feed low-purine diet concurrently. Monitor uric acid levels and hepatic function.
Species references:All Bearded Dragon drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 10–15 mg/kg | q12h | Strong | Denerolle P, Bourdoiseau G. Combination allopurinol and antimony treatment versus antimony alone and allopurinol alone in the treatment of canine leishmaniasis (96 cases). J Vet Intern Med. 1999;13(5):413-415. doi:10.1111/j.1939-1676.1999.tb01455.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.65 (2026-08-01). |
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