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Allopurinol

Zyloprim, Aloprim

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Urinary

Routes

PO

Indications

Gout (uric acid nephropathy)Urate urolithiasis prevention

Mechanism of Action

Inhibits xanthine oxidase, reducing conversion of hypoxanthine to xanthine and xanthine to uric acid. Lowers serum and urinary urate levels.

Side effects & warnings

May cause xanthine urolithiasis if protein intake not controlled. Feed low-purine diet concurrently. Monitor uric acid levels and hepatic function.

Species with Allopurinol dosing data (2 dose rules)

Species references:All Bearded Dragon drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

  • · Carpenter's Exotic Animal Formulary, 6th Ed
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (1 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO10–15 mg/kgq12hStrongPlumb's Veterinary Drug Handbook, 9th Ed

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