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Dog (Domestic)

Canis lupus familiaris

Dog · Typical weight 2.00–80.00 kg

Clinical context for dog dosing

Dogs (Canis lupus familiaris) are the best-characterised veterinary species pharmacologically, with breed-specific genetic variants meaningfully shifting drug safety. The ABCB1 (MDR1) mutation in collie-type breeds, Australian shepherds, long-haired whippets, and others changes the safety profile of ivermectin, loperamide, and several chemotherapeutics — affected-breed warnings are surfaced on every relevant drug page. NSAIDs, isoxazolines, and gabapentin dominate volume; opioid analgesia is well-tolerated with standard titration.

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