Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Nepafenac Ophthalmic is used in dogs for Ocular inflammation, perioperative. Routes documented in dogs: TOPICAL (ophthalmic). A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Nepafenac Ophthalmic in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nevanac
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| TOPICAL (ophthalmic) | NSAID prodrug with good intraocular penetration | q8-12h | 3-7 days perioperative; or as directed | Ocular inflammation, perioperative | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1415 (2026-08-01). |
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NSAID prodrug converted to amfenac by intraocular hydrolases. Inhibits COX-1 and COX-2 in ocular tissues, reducing prostaglandin-mediated inflammation and pain.
Shake well before use. May delay corneal healing. Avoid with corneal ulcers. Used perioperatively and for uveitis. Less corneal toxicity than some older NSAIDs.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Nepafenac Ophthalmic dose range in dogs, with cited source references: TOPICAL (ophthalmic) NSAID prodrug with good intraocular penetration q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Nepafenac Ophthalmic in dogs: TOPICAL (ophthalmic).
Cited course lengths for Nepafenac Ophthalmic in dogs include: 3-7 days perioperative; or as directed. Duration depends on the indication — match it to the specific dose rule in the table above.
Nepafenac Ophthalmic is indicated in dogs for: Ocular inflammation, perioperative.
These are general warnings for Nepafenac Ophthalmic across species; consult the dog dosing table above for species-specific guidance. Shake well before use. May delay corneal healing. Avoid with corneal ulcers. Used perioperatively and for uveitis. Less corneal toxicity than some older NSAIDs.
Why a species-specific page? Nepafenac Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.