Apraclonidine Ophthalmic for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Apraclonidine Ophthalmic is used in dog for Acute glaucoma (short-term IOP reduction). Routes documented in dog: Ophthalmic. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Apraclonidine Ophthalmic in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Iopidine
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Ophthalmic | 0 mg/kg | 1 drop affected eye q8h-q12h | Short-term only (tachyphylaxis develops in 1-2 weeks) | Acute glaucoma (short-term IOP reduction) | Moderate | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Selective alpha-2 adrenergic agonist that reduces aqueous humor production and enhances uveoscleral outflow, lowering intraocular pressure.
Side effects & warnings
Tachyphylaxis develops with chronic use — best for short-term IOP reduction. May cause conjunctival blanching. Minimal systemic absorption.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Ophthalmic drugs with dog dosing
Apraclonidine Ophthalmic dosing in other species
Why a species-specific page? Apraclonidine Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.