Acetylcysteine Ophthalmic for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Acetylcysteine Ophthalmic is used in dog for Melting corneal ulcer (collagenase inhibition). Routes documented in dog: Ophthalmic. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Acetylcysteine Ophthalmic in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Mucomyst Ophthalmic Compounded
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Ophthalmic | 0 mg/kg | 1 drop affected eye q1-2h initially, then q4-6h | Continue until melting stops and epithelial healing begins | Melting corneal ulcer (collagenase inhibition) | Strong | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Thiol compound that inhibits collagenase (matrix metalloproteinases) in melting corneal ulcers. Breaks disulfide bonds in mucus, also reducing mucus viscosity on the corneal surface.
Side effects & warnings
Must be compounded for ophthalmic use. Essential for melting/keratomalacia ulcers. Apply every 1-2 hours initially. Stinging on application. Refrigerate compounded solutions. Short shelf life.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Ophthalmic drugs with dog dosing
Acetylcysteine Ophthalmic dosing in other species
Why a species-specific page? Acetylcysteine Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.