Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Acetylcysteine Ophthalmic is used in dogs for Melting corneal ulcer (collagenase inhibition). Routes documented in dogs: Ophthalmic. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Acetylcysteine Ophthalmic in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Mucomyst Ophthalmic Compounded
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| Ophthalmic | CRITICAL for keratomalacia/melting ulcers | 1 drop affected eye q1-2h initially, then q4-6h | Continue until melting stops and epithelial healing begins | Melting corneal ulcer (collagenase inhibition) | Strong | Ollivier, F.J., Gilger, B.C., Barrie, K.P., et al. (2007) Proteinases of the cornea and preocular tear film. Veterinary Ophthalmology, 10, 199-206. — Verified against Veterinary Ophthalmology (Gelatt), 6th Ed, p.1145 (2026-08-01). |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Thiol compound that inhibits collagenase (matrix metalloproteinases) in melting corneal ulcers. Breaks disulfide bonds in mucus, also reducing mucus viscosity on the corneal surface.
Must be compounded for ophthalmic use. Essential for melting/keratomalacia ulcers. Apply every 1-2 hours initially. Stinging on application. Refrigerate compounded solutions. Short shelf life.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Acetylcysteine Ophthalmic dose range in dogs, with cited source references: Ophthalmic CRITICAL for keratomalacia/melting ulcers 1 drop affected eye q1-2h initially, then q4-6h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Acetylcysteine Ophthalmic in dogs: Ophthalmic.
Cited course lengths for Acetylcysteine Ophthalmic in dogs include: Continue until melting stops and epithelial healing begins. Duration depends on the indication — match it to the specific dose rule in the table above.
Acetylcysteine Ophthalmic is indicated in dogs for: Melting corneal ulcer (collagenase inhibition).
These are general warnings for Acetylcysteine Ophthalmic across species; consult the dog dosing table above for species-specific guidance. Must be compounded for ophthalmic use. Essential for melting/keratomalacia ulcers. Apply every 1-2 hours initially. Stinging on application. Refrigerate compounded solutions. Short shelf life.
Why a species-specific page? Acetylcysteine Ophthalmic pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.