ExoticRx · exoticrx.com/drugs/apraclonidine-ophthalmic
US brand names:Iopidine
Selective alpha-2 adrenergic agonist that reduces aqueous humor production and enhances uveoscleral outflow, lowering intraocular pressure.
Tachyphylaxis develops with chronic use — best for short-term IOP reduction. May cause conjunctival blanching. Minimal systemic absorption.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | See the cited source for the printed regimen | 1 drop affected eye q8h-q12h | Moderate | Plumb's 10th ed printed p.1343, Apraclonidine Ophthalmic monograph.Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.