ExoticRx · exoticrx.com/drugs/besifloxacin-ophthalmic
US brand names:Besivance
8-chloro fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV with balanced dual-targeting activity. Developed exclusively for topical ophthalmic use.
Good activity against resistant staphylococci. No systemic formulation exists, reducing resistance selection pressure. May cause transient conjunctival irritation.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | Broad-spectrum including MRSA/MRSP | 1 drop affected eye q8h | Moderate | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1374 (2026-08-01). |
| Cat (Domestic) | Ophthalmic | Suitable for feline bacterial conjunctivitis | 1 drop affected eye q8h-q12h | Weak | Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1374 (2026-08-01). |
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