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Besifloxacin Ophthalmic

Besivance

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Ophthalmic

Routes

Ophthalmic

Indications

Bacterial conjunctivitiskeratitis

Mechanism of Action

8-chloro fluoroquinolone that inhibits both DNA gyrase and topoisomerase IV with balanced dual-targeting activity. Developed exclusively for topical ophthalmic use.

Side effects & warnings

Good activity against resistant staphylococci. No systemic formulation exists, reducing resistance selection pressure. May cause transient conjunctival irritation.

Species with Besifloxacin Ophthalmic dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Moderate×1Weak×1

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Gelatt KN, Veterinary Ophthalmology, 6th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)Ophthalmic0 mg/kg1 drop affected eye q8hModerateGelatt KN, Veterinary Ophthalmology, 6th Ed
Cat (Domestic)Ophthalmic0 mg/kg1 drop affected eye q8h-q12hWeakGelatt KN, Veterinary Ophthalmology, 6th Ed

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