ExoticRx · exoticrx.com/drugs/atropine-ophthalmic
US brand names:Atropine Ophthalmic Solution
Atropine Ophthalmic is dosed at plumb printed p.1344: "Dosages | Mydriasis and cycloplegia (extra-label): Initially, 1 drop or a " - # inch strip to the a%ected eye(s) 2 to 3 times daily and then once d…" in dogs, per Plumb's Veterinary Drug Handbook, 10th ed — printed p.1343-1344, Atropine Ophthalmic monograph (NOT p.112, which is the systemic Atropine monograph). Verify against current literature before clinical use.
Muscarinic receptor antagonist causing mydriasis (pupil dilation) and cycloplegia (ciliary muscle paralysis). Long duration 1-2 weeks.
CONTRAINDICATED in glaucoma (increases IOP). Bitter taste from nasolacrimal drainage causes profuse salivation especially in cats. Long duration — use judiciously. Reduces tear production.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | plumb printed p.1344: "Dosages | Mydriasis and cycloplegia (extra-label): Initially, 1 drop or a " - # inch strip to the a%ected eye(s) 2 to 3 times daily and then once d…" | q8-24h (1% solution) | Strong | Plumb's Veterinary Drug Handbook, 10th ed — printed p.1343-1344, Atropine Ophthalmic monograph (NOT p.112, which is the systemic Atropine monograph)Compilation only — we have not located an independent source that prints this figure. |
| Cat (Domestic) | Ophthalmic | See the cited source for the printed regimen | q12-24h (1% solution) | Strong | Davis JL, Stewart T, Brazik E, Gilger BC. The effect of topical administration of atropine sulfate on the normal equine pupil: influence of age, breed and gender. Vet Ophthalmol. 2003;6(4):329-332. doi:10.1111/j.1463-5224.2003.00315.x — Plumb's 10th ed printed p.112, Atropine monograph spanning p.112-115. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.