ExoticRx · exoticrx.com/drugs/atropine-ophthalmic
US brand names:Atropine Ophthalmic Solution
Atropine Ophthalmic is dosed at 1 drop per eye in dogs, per Greenberg S, Plummer C, Maisenbacher H, Friary J, Berg A. The effect of topical ophthalmic 1% atropine on heart rate and rhythm in normal dogs. Vet Ophthalmol. 2015;18(2):105-108. doi:10.1111/vop.12125 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1371 (2026-08-01).. Verify against current literature before clinical use.
Muscarinic receptor antagonist causing mydriasis (pupil dilation) and cycloplegia (ciliary muscle paralysis). Long duration 1-2 weeks.
CONTRAINDICATED in glaucoma (increases IOP). Bitter taste from nasolacrimal drainage causes profuse salivation especially in cats. Long duration — use judiciously. Reduces tear production.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | 1 drop per eye | q8-24h (1% solution) | Strong | Greenberg S, Plummer C, Maisenbacher H, Friary J, Berg A. The effect of topical ophthalmic 1% atropine on heart rate and rhythm in normal dogs. Vet Ophthalmol. 2015;18(2):105-108. doi:10.1111/vop.12125 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1371 (2026-08-01). |
| Cat (Domestic) | Ophthalmic | Profuse salivation from bitter taste via nasolacrimal duct | q12-24h (1% solution) | Strong | Davis JL, Stewart T, Brazik E, Gilger BC. The effect of topical administration of atropine sulfate on the normal equine pupil: influence of age, breed and gender. Vet Ophthalmol. 2003;6(4):329-332. doi:10.1111/j.1463-5224.2003.00315.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1371 (2026-08-01). |
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