Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Procainamide is used in dog for Ventricular tachyarrhythmias, Ventricular arrhythmias (maintenance). Routes documented in dog: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Procainamide in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Pronestyl, Procanbid
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 2–4 mg/kg | IV bolus over 3-5 min, then CRI 10-40 mcg/kg/min | Until arrhythmia controlled | Ventricular tachyarrhythmias | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–30 mg/kg | q6-8h | Long-term | Ventricular arrhythmias (maintenance) | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
One of the cited rules is a continuous-rate-infusion regimen: IV 2–4 mg/kg IV bolus over 3-5 min, then CRI 10-40 mcg/kg/min. CRI regimens are delivered as a continuous infusion rather than discrete doses — verify the rate against the cited source before use.
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Class IA antiarrhythmic blocking fast sodium channels. Prolongs action potential duration and effective refractory period in atria and ventricles.
GI upset common. Drug-induced lupus (SLE) with chronic use. Monitor CBC, ANA. N-acetylprocainamide (NAPA) metabolite has Class III activity.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Procainamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.