Cat · Felis catus · typical adult weight 2.50–7.00 kg
Procainamide is dosed at 1–2 mg/kg IV IV slowly in cats, per Estrada A. Which drugs treat ventricular arrhythmias in dogs and cats? Plumb’s Therapeutics Brief. Published online 2015:24-29. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1097 (2026-08-01). — Plumb's 10th ed (held) printed p.1070, Procainamide monograph spanning p.1068-1070; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Procainamide is used in cats for Ventricular tachycardia. Routes documented in cats: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Procainamide in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pronestyl, Procanbid
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 1–2 mg/kg | IV slowly | Emergency | Ventricular tachycardia | Weak | Estrada A. Which drugs treat ventricular arrhythmias in dogs and cats? Plumb’s Therapeutics Brief. Published online 2015:24-29. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1097 (2026-08-01). — Plumb's 10th ed (held) printed p.1070, Procainamide monograph spanning p.1068-1070; page located 2026-08-05 from the book's own running heads, and carries this exact dose under the matching species heading. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mcg/kg) | Route | Source | As printed |
|---|---|---|---|
| 10–20 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.705 | • CRI: 1-2 mg/kg IV slowly, then 10-20 mcg/kg/min IV. |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 3–8 | IM | Papich Saunders Handbook of Veterinary Drugs, 4th edp.705 | • 3-8 mg/kg q6-8h IM or PO. |
| 1–2 | IV | Papich Saunders Handbook of Veterinary Drugs, 4th edp.705 | • CRI: 1-2 mg/kg IV slowly, then 10-20 mcg/kg/min IV. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Class IA antiarrhythmic blocking fast sodium channels. Prolongs action potential duration and effective refractory period in atria and ventricles.
GI upset common. Drug-induced lupus (SLE) with chronic use. Monitor CBC, ANA. N-acetylprocainamide (NAPA) metabolite has Class III activity.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Procainamide dose range in cats, with cited source references: IV 1–2 mg/kg IV slowly. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Procainamide in cats: IV.
Cited course lengths for Procainamide in cats include: Emergency. Duration depends on the indication — match it to the specific dose rule in the table above.
Procainamide is indicated in cats for: Ventricular tachycardia.
These are general warnings for Procainamide across species; consult the cat dosing table above for species-specific guidance. GI upset common. Drug-induced lupus (SLE) with chronic use. Monitor CBC, ANA. N-acetylprocainamide (NAPA) metabolite has Class III activity.
Why a species-specific page? Procainamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.