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Bretylium for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Bretylium is used in cat for Ventricular fibrillation (refractory). Routes documented in cat: IV. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Bretylium in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Bretylol

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV5–10 mg/kgOnceEmergency use onlyVentricular fibrillation (refractory)ExtrapolatedPlumb's Veterinary Drug Handbook, 9th Ed

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Mechanism of action

Adrenergic neuronal blocking agent and Class III antiarrhythmic that prolongs action potential duration and refractory period.

Side effects & warnings

Initial transient release of norepinephrine may cause hypertension. Hypotension common after bolus. Reserved for life-threatening ventricular arrhythmias.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Cardiovascular drugs with cat dosing

Bretylium dosing in other species

Why a species-specific page? Bretylium pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.