ExoticRx · exoticrx.com/drugs/bretylium
US brand names:Bretylol
Bretylium is dosed at 5–10 mg/kg IV Once, may repeat in 20 min in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Adrenergic neuronal blocking agent and Class III antiarrhythmic that prolongs action potential duration and refractory period.
Initial transient release of norepinephrine may cause hypertension. Hypotension common after bolus. Reserved for life-threatening ventricular arrhythmias.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 5–10 mg/kg | Once, may repeat in 20 min | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 5–10 mg/kg | Once | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.