Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Bretylium is dosed at 5–10 mg/kg IV Once, may repeat in 20 min in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Bretylium is used in dogs for Ventricular fibrillation/tachycardia (refractory). Routes documented in dogs: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Bretylium in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Bretylol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | Once, may repeat in 20 min | Emergency use only; single or few doses | Ventricular fibrillation/tachycardia (refractory) | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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Adrenergic neuronal blocking agent and Class III antiarrhythmic that prolongs action potential duration and refractory period.
Initial transient release of norepinephrine may cause hypertension. Hypotension common after bolus. Reserved for life-threatening ventricular arrhythmias.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Bretylium dose range in dogs, with cited source references: IV 5–10 mg/kg Once, may repeat in 20 min. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Bretylium in dogs: IV.
Cited course lengths for Bretylium in dogs include: Emergency use only; single or few doses. Duration depends on the indication — match it to the specific dose rule in the table above.
Bretylium is indicated in dogs for: Ventricular fibrillation/tachycardia (refractory).
These are general warnings for Bretylium across species; consult the dog dosing table above for species-specific guidance. Initial transient release of norepinephrine may cause hypertension. Hypotension common after bolus. Reserved for life-threatening ventricular arrhythmias.
Why a species-specific page? Bretylium pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.