Amiloride for Dog
Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amiloride is used in dog for Potassium-sparing diuresis (adjunct). Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Amiloride in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Midamor
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–0.3 mg/kg | q12-24h | Long-term; monitor potassium | Potassium-sparing diuresis (adjunct) | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
Need the exact dose for your patient?
These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Directly blocks epithelial sodium channels (ENaC) in the distal nephron, reducing sodium reabsorption and decreasing potassium and hydrogen ion secretion.
Side effects & warnings
Hyperkalemia risk. Weak diuretic alone — usually combined with thiazide or loop diuretic. Avoid in severe renal impairment.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Cardiovascular drugs with dog dosing
Amiloride dosing in other species
Why a species-specific page? Amiloride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.