Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amiloride is dosed at 0.1–0.3 mg/kg PO q12-24h in dogs, per Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.33 (2026-08-01).. Amiloride is used in dogs for Potassium-sparing diuresis (adjunct). Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Amiloride in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Midamor
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–0.3 mg/kg | q12-24h | Long-term; monitor potassium | Potassium-sparing diuresis (adjunct) | Weak | Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.33 (2026-08-01). |
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Directly blocks epithelial sodium channels (ENaC) in the distal nephron, reducing sodium reabsorption and decreasing potassium and hydrogen ion secretion.
Hyperkalemia risk. Weak diuretic alone — usually combined with thiazide or loop diuretic. Avoid in severe renal impairment.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amiloride dose range in dogs, with cited source references: PO 0.1–0.3 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amiloride in dogs: PO.
Cited course lengths for Amiloride in dogs include: Long-term; monitor potassium. Duration depends on the indication — match it to the specific dose rule in the table above.
Amiloride is indicated in dogs for: Potassium-sparing diuresis (adjunct).
These are general warnings for Amiloride across species; consult the dog dosing table above for species-specific guidance. Hyperkalemia risk. Weak diuretic alone — usually combined with thiazide or loop diuretic. Avoid in severe renal impairment.
Why a species-specific page? Amiloride pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.