Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amlodipine Besylate is dosed at 0.1–0.5 mg/kg PO q24h in dogs, per Acierno MJ, Brown S, Coleman AE, et al. ACVIM consensus statement: guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med. 2018;32:1803-1822. / 26. Keene BW, Atkins CE, Bonagura JD, et al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. J Vet Intern Med. 2019;33:1127-1140. doi:10.1111/jvim.15331 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.91 (2026-08-01). — Plumb's 10th ed (held) printed p.62, Amlodipine monograph spanning p.62-64; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Amlodipine Besylate is used in dogs for Systemic hypertension. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Amlodipine Besylate in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Norvasc, Amodip
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–0.5 mg/kg | q24h | Long-term | Systemic hypertension | Moderate | Acierno MJ, Brown S, Coleman AE, et al. ACVIM consensus statement: guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med. 2018;32:1803-1822. / 26. Keene BW, Atkins CE, Bonagura JD, et al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. J Vet Intern Med. 2019;33:1127-1140. doi:10.1111/jvim.15331 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.91 (2026-08-01). — Plumb's 10th ed (held) printed p.62, Amlodipine monograph spanning p.62-64; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/animal) | Route | Source | As printed |
|---|---|---|---|
| 2.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.64 | • 2.5 mg/dog or 0.1-0.5 mg/kg q24h PO. The higher dose of 0.5 mg/kg may be |
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.05–0.1 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.40 | Initial dose 0.05-0.1 mg/kg p.o. q12-24h. The dose may be titrated upwards weekly as required, up to 0.5 mg/kg, |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Selectively blocks L-type calcium channels in vascular smooth muscle causing vasodilation. Reduces systemic vascular resistance and blood pressure.
First-line antihypertensive in cats. Dose-dependent hypotension. Gingival hyperplasia reported in dogs. Monitor blood pressure regularly.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amlodipine Besylate dose range in dogs, with cited source references: PO 0.1–0.5 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amlodipine Besylate in dogs: PO.
Cited course lengths for Amlodipine Besylate in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Amlodipine Besylate is indicated in dogs for: Systemic hypertension.
These are general warnings for Amlodipine Besylate across species; consult the dog dosing table above for species-specific guidance. First-line antihypertensive in cats. Dose-dependent hypotension. Gingival hyperplasia reported in dogs. Monitor blood pressure regularly.
Why a species-specific page? Amlodipine Besylate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 0.5 |
| — |
| BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.40 |
| dose may be titrated upwards weekly as required, up to 0.5 mg/kg, monitoring blood pressure regularly |
| 0.1–0.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.64 | • 2.5 mg/dog or 0.1-0.5 mg/kg q24h PO. The higher dose of 0.5 mg/kg may be |
| 0.5 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.64 | • 2.5 mg/dog or 0.1-0.5 mg/kg q24h PO. The higher dose of 0.5 mg/kg may be |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.