Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amiodarone is dosed at 5–10 mg/kg IV IV loading over 30-60 min in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Amiodarone is used in dogs for Life-threatening ventricular arrhythmias, Refractory ventricular arrhythmias. Routes documented in dogs: IV, PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Amiodarone in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Cordarone, Pacerone
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IV | 5–10 mg/kg | IV loading over 30-60 min | Emergency | Life-threatening ventricular arrhythmias | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–15 mg/kg | q12h loading x 7d, then q24h | Long-term | Refractory ventricular arrhythmias | Moderate | Saunders AB, Miller MW, Gordon SG, Van De Wiele CM. Oral amiodarone therapy in dogs with atrial fibrillation. J Vet Intern Med. 2006;20(4):921-926. doi:10.1111/j.1939-1676.2006.tb01806.x — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.85 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Class III antiarrhythmic blocking potassium, sodium, and calcium channels plus beta-adrenergic receptors. Prolongs action potential duration and refractory period.
Very long half-life (weeks). Hepatotoxicity, pulmonary fibrosis, thyroid dysfunction (contains iodine). Monitor liver, thyroid, and lung function. Numerous drug interactions.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amiodarone dose ranges in dogs, with cited source references: IV 5–10 mg/kg IV loading over 30-60 min; PO 10–15 mg/kg q12h loading x 7d, then q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amiodarone in dogs: IV, PO.
Cited course lengths for Amiodarone in dogs include: Emergency; Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Amiodarone is indicated in dogs for: Life-threatening ventricular arrhythmias, Refractory ventricular arrhythmias.
These are general warnings for Amiodarone across species; consult the dog dosing table above for species-specific guidance. Very long half-life (weeks). Hepatotoxicity, pulmonary fibrosis, thyroid dysfunction (contains iodine). Monitor liver, thyroid, and lung function. Numerous drug interactions.
Why a species-specific page? Amiodarone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.