Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Captopril is dosed at 0.5–2 mg/kg PO q8-12h in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.134 (2026-08-01).. Captopril is used in dogs for Congestive heart failure / hypertension. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Captopril in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Capoten
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–2 mg/kg | q8-12h | Long-term; monitor renal function at 1 week, then periodically | Congestive heart failure / hypertension | Moderate | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.134 (2026-08-01). |
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Inhibits angiotensin-converting enzyme, reducing angiotensin II and aldosterone levels, thereby decreasing peripheral resistance and blood pressure.
Monitor renal function and electrolytes. May cause hypotension, hyperkalemia. Adjust dose in renal impairment.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Captopril dose range in dogs, with cited source references: PO 0.5–2 mg/kg q8-12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Captopril in dogs: PO.
Cited course lengths for Captopril in dogs include: Long-term; monitor renal function at 1 week, then periodically. Duration depends on the indication — match it to the specific dose rule in the table above.
Captopril is indicated in dogs for: Congestive heart failure / hypertension.
These are general warnings for Captopril across species; consult the dog dosing table above for species-specific guidance. Monitor renal function and electrolytes. May cause hypotension, hyperkalemia. Adjust dose in renal impairment.
Why a species-specific page? Captopril pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.