Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Digoxin is used in dog for Supraventricular tachycardia, dilated cardiomyopathy. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Digoxin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Lanoxin, Cardoxin
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.005–0.01 mg/kg | q12h | Long-term (serum level guided) | Supraventricular tachycardia, dilated cardiomyopathy | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits Na+/K+-ATPase, increasing intracellular calcium, enhancing contractility (positive inotrope). Also slows AV conduction (vagomimetic).
NARROW therapeutic index. Monitor serum digoxin levels (target 1.0-2.0 ng/ml dogs). Toxicity: arrhythmias, anorexia, vomiting. Reduce dose in renal failure. Many drug interactions (quinidine, verapamil).
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Digoxin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.