Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Cilostazol is dosed at 2–5 mg/kg PO q12h in dogs, per Corroborated 2026-07-31: Ohmori T, Matsumura Y, Yoshimura A, et al. Front Vet Sci 2022;9:954295. doi:10.3389/fvets.2022.954295 PMID:36061105 - dog, cilostazol 5-10 mg/kg PO q12h (59-dog retrospective series; range 3.5-37.5 mg/kg/day). Studied for BRADYARRHYTHMIA only; thrombosis indication is extrapolated.. Cilostazol is used in dogs for Peripheral vascular disease / thrombosis adjunct. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Cilostazol in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Pletal
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2–5 mg/kg | q12h | Long-term; investigational | Peripheral vascular disease / thrombosis adjunct | Weak | Corroborated 2026-07-31: Ohmori T, Matsumura Y, Yoshimura A, et al. Front Vet Sci 2022;9:954295. doi:10.3389/fvets.2022.954295 PMID:36061105 - dog, cilostazol 5-10 mg/kg PO q12h (59-dog retrospective series; range 3.5-37.5 mg/kg/day). Studied for BRADYARRHYTHMIA only; thrombosis indication is extrapolated. |
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Selective phosphodiesterase-3 inhibitor that increases cAMP in platelets and vascular smooth muscle, inhibiting platelet aggregation and causing vasodilation.
Contraindicated in heart failure. Headache, diarrhea. Avoid with CYP3A4 and CYP2C19 inhibitors. Limited veterinary use for peripheral vascular disease.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cilostazol dose range in dogs, with cited source references: PO 2–5 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cilostazol in dogs: PO.
Cited course lengths for Cilostazol in dogs include: Long-term; investigational. Duration depends on the indication — match it to the specific dose rule in the table above.
Cilostazol is indicated in dogs for: Peripheral vascular disease / thrombosis adjunct.
These are general warnings for Cilostazol across species; consult the dog dosing table above for species-specific guidance. Contraindicated in heart failure. Headache, diarrhea. Avoid with CYP3A4 and CYP2C19 inhibitors. Limited veterinary use for peripheral vascular disease.
Why a species-specific page? Cilostazol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.