ExoticRx · exoticrx.com/drugs/cilostazol
US brand names:Pletal
Cilostazol is dosed at 2–5 mg/kg PO q12h in dogs, per Corroborated 2026-07-31: Ohmori T, Matsumura Y, Yoshimura A, et al. Front Vet Sci 2022;9:954295. doi:10.3389/fvets.2022.954295 PMID:36061105 - dog, cilostazol 5-10 mg/kg PO q12h (59-dog retrospective series; range 3.5-37.5 mg/kg/day). Studied for BRADYARRHYTHMIA only; thrombosis indication is extrapolated. — https://doi.org/10.3389/fvets.2022.954295. Verify against current literature before clinical use.
Selective phosphodiesterase-3 inhibitor that increases cAMP in platelets and vascular smooth muscle, inhibiting platelet aggregation and causing vasodilation.
Contraindicated in heart failure. Headache, diarrhea. Avoid with CYP3A4 and CYP2C19 inhibitors. Limited veterinary use for peripheral vascular disease.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2–5 mg/kg | q12h | Weak | Corroborated 2026-07-31: Ohmori T, Matsumura Y, Yoshimura A, et al. Front Vet Sci 2022;9:954295. doi:10.3389/fvets.2022.954295 PMID:36061105 - dog, cilostazol 5-10 mg/kg PO q12h (59-dog retrospective series; range 3.5-37.5 mg/kg/day). Studied for BRADYARRHYTHMIA only; thrombosis indication is extrapolated. — https://doi.org/10.3389/fvets.2022.954295 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.