Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Clopidogrel is dosed at 1–2 mg/kg PO q24h in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.206 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.206' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.178; verified by finding the drug named there. If you are holding the book, turn to p.178. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855. Clopidogrel is used in dogs for Antiplatelet therapy. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Clopidogrel in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Plavix
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 1–2 mg/kg | q24h | Long-term | Antiplatelet therapy | Moderate | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.206 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.206' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.178; verified by finding the drug named there. If you are holding the book, turn to p.178. — SOURCE EDITION: Saunders Handbook of Veterinary Drugs — ISBN 9780323244855, https://openlibrary.org/isbn/9780323244855 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
The sources disagree for this combination. The ranges below do not overlap on a comparable route. This is not an error in one of them — published veterinary references differ, and reconciling them for a particular patient is a clinical judgement.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 1.1–4 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.113 | 1.1-4 mg/kg p.o. q24h. A single loading dose of 4-10 mg/kg p.o. may help achieve therapeutic concentr |
| 4–10 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.113 | 1.1-4 mg/kg p.o. q24h. A single loading dose of 4-10 mg/kg p.o. may help achieve therapeutic concentrations more rapidly |
| 2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.206 | • 2 mg/kg q24h PO. |
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Irreversibly blocks the P2Y12 ADP receptor on platelet surface, preventing ADP-mediated platelet activation and aggregation.
Primary use in cats: prevention of arterial thromboembolism (ATE) in cardiomyopathy. Give with food. Bleeding risk. Takes 3-5 days for full antiplatelet effect. Preferred over aspirin in cats.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Clopidogrel dose range in dogs, with cited source references: PO 1–2 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Clopidogrel in dogs: PO.
Cited course lengths for Clopidogrel in dogs include: Long-term. Duration depends on the indication — match it to the specific dose rule in the table above.
Clopidogrel is indicated in dogs for: Antiplatelet therapy.
These are general warnings for Clopidogrel across species; consult the dog dosing table above for species-specific guidance. Primary use in cats: prevention of arterial thromboembolism (ATE) in cardiomyopathy. Give with food. Bleeding risk. Takes 3-5 days for full antiplatelet effect. Preferred over aspirin in cats.
Why a species-specific page? Clopidogrel pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.
| 2–4 |
| PO |
| Papich Saunders Handbook of Veterinary Drugs, 4th edp.206 |
| • An oral loading dose may be given at 2-4 mg/kg followed by 1-2 mg/kg q24h |
| 1–2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.206 | • An oral loading dose may be given at 2-4 mg/kg followed by 1-2 mg/kg q24h |
| 10 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.206 | PO. (In some cases, a higher oral loading dose of 10 mg/kg has been used.) |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.