ExoticRx · exoticrx.com/drugs/clopidogrel
US brand names:Plavix
Clopidogrel is dosed at 1–2 mg/kg PO q24h in dogs, per Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.206 (2026-08-01).. Verify against current literature before clinical use.
Irreversibly blocks the P2Y12 ADP receptor on platelet surface, preventing ADP-mediated platelet activation and aggregation.
Primary use in cats: prevention of arterial thromboembolism (ATE) in cardiomyopathy. Give with food. Bleeding risk. Takes 3-5 days for full antiplatelet effect. Preferred over aspirin in cats.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q24h | Moderate | Verified against Papich/Saunders Handbook of Veterinary Drugs, 4th Ed, p.206 (2026-08-01). |
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