Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Enrofloxacin is used in dog for Bacterial infections when oral not feasible, Severe systemic infections, Complicated UTI, pyelonephritis, Pneumonia (community-acquired). Routes documented in dog: IM, IV, PO, SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 9 cited dose rules for Enrofloxacin in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Baytril
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 5–10 mg/kg | q24h | 5-10 days | Bacterial infections when oral not feasible | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| IV | 5–10 mg/kg | q24h | Until oral feasible | Severe systemic infections | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–20 mg/kg | q24h | 14-28 days | Complicated UTI, pyelonephritis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–20 mg/kg | q24h | 10-14 days minimum; extend if unresolved | Pneumonia (community-acquired) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–20 mg/kg | q24h | 4-6 weeks minimum | Otitis media/interna | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 5–20 mg/kg | q24h | 7-14 days | Bacterial infections (skin, UTI, respiratory) | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–20 mg/kg | q24h | 28-42 days | Prostatitis | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
| PO | 10–20 mg/kg | q24h | 6-8 weeks minimum | Osteomyelitis | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| SC | 5–10 mg/kg | q24h | 7-14 days | Bacterial infections when oral not feasible | Strong | Plumb's Veterinary Drug Handbook, 9th Ed |
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Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.
Avoid in growing animals (cartilage damage). Do NOT use in cats at doses >5mg/kg (retinal toxicity). Avoid concurrent use with theophylline.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Enrofloxacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.