Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Amoxicillin-Clavulanate is dosed at 12.5–25 mg/kg PO q12h in dogs, per Weese JS, Blondeau J, Boothe D, et al. International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats. Vet J. 2019;247:8-25. doi:10.1016/j.tvjl.2019.02.008; Hillier A, Lloyd DH, Weese JS, et al. Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis. Vet Dermatol. 2014;25(3):163-e43. doi:10.1111/vde.12168 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.99 (2026-08-01).. Amoxicillin-Clavulanate is used in dogs for Skin infections, UTI, dental, respiratory. Routes documented in dogs: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Amoxicillin-Clavulanate in dogs, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Clavamox, Augmentin
Contraindicated in Rabbit, Guinea Pig, Chinchilla, Hamster, Degu
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 12.5–25 mg/kg | q12h | 7-14 days | Skin infections, UTI, dental, respiratory | Strong | Weese JS, Blondeau J, Boothe D, et al. International Society for Companion Animal Infectious Diseases (ISCAID) guidelines for the diagnosis and management of bacterial urinary tract infections in dogs and cats. Vet J. 2019;247:8-25. doi:10.1016/j.tvjl.2019.02.008; Hillier A, Lloyd DH, Weese JS, et al. Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis. Vet Dermatol. 2014;25(3):163-e43. doi:10.1111/vde.12168 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.99 (2026-08-01). |
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Amoxicillin inhibits cell wall synthesis; clavulanate irreversibly inhibits beta-lactamase, extending spectrum to beta-lactamase-producing organisms.
CONTRAINDICATED in rabbits, guinea pigs, hamsters (fatal dysbiosis). GI upset (vomiting, diarrhea). Broad-spectrum first-line antibiotic. Give with food.
Species-specific contraindications and adverse-reaction reports for dogs may differ from canine / feline reference data — consult the primary citations listed with each rule.
Amoxicillin-Clavulanate dose range in dogs, with cited source references: PO 12.5–25 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Amoxicillin-Clavulanate in dogs: PO.
Cited course lengths for Amoxicillin-Clavulanate in dogs include: 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Amoxicillin-Clavulanate is indicated in dogs for: Skin infections, UTI, dental, respiratory.
These are general warnings for Amoxicillin-Clavulanate across species; consult the dog dosing table above for species-specific guidance. CONTRAINDICATED in rabbits, guinea pigs, hamsters (fatal dysbiosis). GI upset (vomiting, diarrhea). Broad-spectrum first-line antibiotic. Give with food.
Why a species-specific page? Amoxicillin-Clavulanate pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dogs — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.