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Amoxicillin-Clavulanate

Clavamox, Augmentin

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antibiotic

Routes

PO

Indications

abscessabscess (non-respiratory)bite woundsdentalrespiratorySkin infectionsSkin/soft tissue infectionUTI

Mechanism of Action

Amoxicillin inhibits cell wall synthesis; clavulanate irreversibly inhibits beta-lactamase, extending spectrum to beta-lactamase-producing organisms.

Side effects & warnings

CONTRAINDICATED in rabbits, guinea pigs, hamsters (fatal dysbiosis). GI upset (vomiting, diarrhea). Broad-spectrum first-line antibiotic. Give with food.

Species with Amoxicillin-Clavulanate dosing data (5 dose rules)

African Pygmy HedgehogCat (Domestic)Dog (Domestic)FerretPet Rat

Species references:All African Pygmy Hedgehog drugsAll Cat (Domestic) drugsAll Dog (Domestic) drugsAll Ferret drugsAll Pet Rat drugs

Evidence levels across 5 dose rules

Strong×2Moderate×3

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 4 published sources

  • · ExoticRx 2026 (ferret dosing guide); Carpenter 6e
  • · ExoticRx 2026 (hedgehog dosing guide); Carpenter 6e
  • · ExoticRx 2026 (rat dosing guide); Carpenter 6e
  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 5 cited rules)

A dog/cat sample is shown here. Cited dosing for all 5 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Dog (Domestic)PO12.5–25 mg/kgq12hStrongPlumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)PO12.5–25 mg/kgq12hStrongPlumb's Veterinary Drug Handbook, 9th Ed

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Calculate Dosage for Amoxicillin-Clavulanate