Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.
Amikacin is dosed at 8–16 mg/kg SC, IM, IV q24h in rabbits, per Plumb's Veterinary Drug Handbook, 10th ed (2023), Amikacin, Systemic, Dosages, printed p.50, entry a) under RABBITS: "8 - 16 mg/kg SC, IM, or IV daily dose (may be divided and given every 8-24 hours). Increased […]" ref 39 = Ivey E, Morrisey J. Therapeutics for rabbits. Vet Clin North Am Exotic Anim Pract. 2000;3(1):183-216 (resolved via plumbref). — Plumb's 10th ed printed p.1341, Amikacin Ophthalmic monograph. Verify against current literature before clinical use.
Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Sample dosing (2 of 39 cited rules)
A dog/cat sample is shown here. Cited dosing for all 35 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
· 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.770 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).
· 15. Barten SL. The medical care of iguanas and other common pet lizards. Vet Clin North Am Small Anim Pract. 1993;23:1213-1249. | 316. Stahl SJ. Pet lizard conditions and syndromes. Semin Avian Exot Pet Med. 2003;12:162-182. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1401
· 241. Dorrestein GM. Passerine and softbill therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:35-57. | 790. Rupiper DJ, Ehrenberg M. Introduction to pigeon practice. Proc Annu Conf Assoc Avian Vet; 1994:203-211. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.1016/s1094-9194(17)30094-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a).
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241. Dorrestein GM. Passerine and softbill therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:35-57. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.1016/s1094-9194(17)30094-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a).
· 360. Gronwall R, Brown MP, Clubb S. Pharmacokinetics of amikacin in African gray parrots. Am J Vet Res. 1989;50:250-252. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.2460/ajvr.1989.50.02.250 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a).
· 360. Gronwall R, Brown MP, Clubb S. Pharmacokinetics of amikacin in African gray parrots. Am J Vet Res. 1989;50:250-252.; 555. Lumeij JT. Psittacine antimicrobial therapy Antimicrobial Therapy in Caged Birds and Exotic Pets, Veterinary Learning Systems, Trenton, NJ; 1995:38-48.; 736. Ramsay EC, Vulliet R. Pharmacokinetic properties of gentamicin and amikacin in the cockatiel. Avian Dis. 1993;37:628-634.; 840. Schroeder EC, Frazier DL, Morris PJ, et al. Pharmacokinetics of ticarcillin and amikacin in blue-fronted Amazon parrots (Amazona aestiva aestiva). J Avian Med Surg. 1997;11:260-267. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.2460/ajvr.1989.50.02.250 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a).
· 444. Stahl SJ. Pet lizard conditions and syndromes. Semin Avian Exot Pet Med. 2003;12:162-182. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.212 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b).
· 45. Lightfoot T. Therapeutics of African pygmy hedgehogs and prairie dogs. Vet Clin North Am Exot Anim Pract. 2000;3:155-172. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.732 doi:10.1016/s1094-9194(17)30099-3 — Carpenter's Exotic Animal Formulary 6th ed, Table 8.1 (Antimicrobial Agents Used in Hedgehogs).
· Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds): '10-20 mg/kg IM, IV q8-12h360,555,736,840 | African grey parrots, Amazon parrots, cockatiels, cockatoos/PK'. Superscript 840 = Schroeder EC, Frazier DL, Morris PJ, et al. Pharmacokinetics of ticarcillin and amikacin in blue-fronted Amazon parrots (Amazona aestiva aestiva). J Avian Med Surg. 1997,11:260-267 - one of the four references on this row.
· Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary, 6th ed, Table 4.1. NOTE: the served figure was matched against the table as a whole, not against this drug's own row, so confirm the number on the page before relying on it. — CORROBORATED 2026-08-06 by independent literature: Amikacin pharmacokinetics and the effects of ambient temperature on the dosage regimen in ball pythons (Python regius). (Journal of zoo and wildlife medicine: official publication of the American Association of Zoo Veterinarians, 1997). PMID:9226620. https://pubmed.ncbi.nlm.nih.gov/9226620/. The paper reports this drug at this dose in this species: "perature on the dosage regimen in ball pythons (Python regius). The serum concentration of amikacin […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct.
· Dorrestein GM. Antimicrobial drug use in companion birds. In: PrescottJF, Baggot JD, Walker RD, eds. Antimicrobial Therapy in Veterinary Medicine, 3rd ed., Iowa State University Press, Ames, IA; 2000:617-636. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a).
· Dorrestein GM. Passerine and softbill therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:35-57. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.1016/s1094-9194(17)30094-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a).
· El-Gammal AA, Ravis WR, Krista LM, et al. Pharmacokinetics and intramuscular bioavailability of amikacin in chickens following single and multiple dosing. J Vet Pharmacol Therap. 1992;15:133-142. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.617 doi:10.1111/j.1365-2885.1992.tb01000.x — Carpenter's Exotic Animal Formulary 6th ed, Table 6.1 (Antimicrobial Agents Used in Backyard Poultry, Gamebirds, and Waterfowl.a,b).
· Gronwall R, Brown MP, Clubb S. Pharmacokinetics of amikacin in African gray parrots. Am J Vet Res. 1989;50:250-252. doi:10.2460/ajvr.1989.50.02.250 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a).
· Hiebert K, Knych H, Hawkins S. Subcutaneous amikacin administration in red-eared sliders (Trachemys scripta elegans) produces prolonged detectable plasma concentrations without biochemistry evidence of impaired renal function. Am J Vet Res. 2024;85(9):ajvr.24.03.0088. doi:10.2460/ajvr.24.03.0088https://europepmc.org/abstract/MED/38901454
· Mcclure JT, Rosin E. Comparison of amikacin dosing regimens in neutropenic guinea pigs with Escherichia coli infection. Am J Vet Res. 1998;59:750-755. doi:10.2460/ajvr.1998.59.06.750 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).
· Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.770 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a).
· Morrisey JK, Carpenter JW, et al. Formulary. In: Quesenberry KE, Orcutt CJ, Mans C, et al. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.703 — Carpenter's Exotic Animal Formulary 6th ed, Table 7.1 (Antimicrobial and Antifungal Agents Used in Sugar Gliders).
· Plumb's 10th ed printed p.1341, Amikacin Ophthalmic monograph.
· Plumb's Veterinary Drug Handbook, 10th ed (2023), Amikacin, Systemic, Dosages, printed p.50, entry a) under RABBITS: "8 - 16 mg/kg SC, IM, or IV daily dose (may be divided and given every 8-24 hours). Increased […]" ref 39 = Ivey E, Morrisey J. Therapeutics for rabbits. Vet Clin North Am Exotic Anim Pract. 2000;3(1):183-216 (resolved via plumbref). — Plumb's 10th ed printed p.1341, Amikacin Ophthalmic monograph.
· Plumb's Veterinary Drug Handbook, 10th ed (2023), p.76-77 — Amikacin, Systemic, Dosages, HORSES (adults) — Plumb's 10th ed printed p.1341, Amikacin Ophthalmic monograph.
· Plumb's Veterinary Drug Handbook, 10th ed, Amikacin Systemic monograph, printed p.49, DOGS - "Susceptible infections and empirical therapy (extra-label): 15 - 30 mg/kg IV, IM, SC once daily." ISBN 9781394172207
· Plumb's Veterinary Drug Handbook, 10th ed, Amikacin Systemic monograph, printed p.50, HORSES - treatment of septic joints, intra-articular. ISBN 9781394172207