Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.
Amikacin is dosed at 3.48 mg/kg IM once (single dose; t1/2 ~4.5 d) in ball pythons, per Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary, 6th ed, Table 4.1 (corpus PDF pp.212-215); located 2026-08-06 by chapter-governed table: this table is in the chapter covering this species and names this drug. NOTE: the served figure was matched against the table as a whole, not against this drug's own row, so confirm the number on the page before relying on it. The held copy has no printed page numbers, so the numbered table is the citable location. — CORROBORATED 2026-08-06 by independent literature: Amikacin pharmacokinetics and the effects of ambient temperature on the dosage regimen in ball pythons (Python regius). (Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 1997). PMID:9226620. https://pubmed.ncbi.nlm.nih.gov/9226620/. The paper reports this drug at this dose in this species: "perature on the dosage regimen in ball pythons (Python regius). The serum concentration of amikacin […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, . Verify against current literature before clinical use.
Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by 27 published sources
· 122. Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.770 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· 15. Barten SL. The medical care of iguanas and other common pet lizards. Vet Clin North Am Small Anim Pract. 1993;23:1213-1249. | 316. Stahl SJ. Pet lizard conditions and syndromes. Semin Avian Exot Pet Med. 2003;12:162-182. — Source: Mader's Reptile and Amphibian Medicine and Surgery, 3rd Ed, p.1401 — SOURCE EDITION: Mader's Reptile and Amphibian Medicine and Surgery (Divers & Stahl) — ISBN 9780323482530, https://openlibrary.org/isbn/9780323482530
Sample dosing (2 of 39 cited rules)
A dog/cat sample is shown here. Cited dosing for all 35 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01). — Plumb's 10th ed (held) printed p.1341, Amikacin Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207
Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01). — Plumb's 10th ed (held) printed p.1341, Amikacin Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207
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241. Dorrestein GM. Passerine and softbill therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:35-57. | 790. Rupiper DJ, Ehrenberg M. Introduction to pigeon practice. Proc Annu Conf Assoc Avian Vet; 1994:203-211. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.1016/s1094-9194(17)30094-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· 241. Dorrestein GM. Passerine and softbill therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:35-57. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.1016/s1094-9194(17)30094-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· 360. Gronwall R, Brown MP, Clubb S. Pharmacokinetics of amikacin in African gray parrots. Am J Vet Res. 1989;50:250-252. ; 555. Lumeij JT. Psittacine antimicrobial therapy Antimicrobial Therapy in Caged Birds and Exotic Pets, Veterinary Learning Systems, Trenton, NJ; 1995:38-48. ; 736. Ramsay EC, Vulliet R. Pharmacokinetic properties of gentamicin and amikacin in the cockatiel. Avian Dis. 1993;37:628-634. ; 840. Schroeder EC, Frazier DL, Morris PJ, et al. Pharmacokinetics of ticarcillin and amikacin in blue-fronted Amazon parrots (Amazona aestiva aestiva). J Avian Med Surg. 1997;11:260-267. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.2460/ajvr.1989.50.02.250 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· 360. Gronwall R, Brown MP, Clubb S. Pharmacokinetics of amikacin in African gray parrots. Am J Vet Res. 1989;50:250-252. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.2460/ajvr.1989.50.02.250 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· 444. Stahl SJ. Pet lizard conditions and syndromes. Semin Avian Exot Pet Med. 2003;12:162-182. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.212 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· 45. Lightfoot T. Therapeutics of African pygmy hedgehogs and prairie dogs. Vet Clin North Am Exot Anim Pract. 2000;3:155-172. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.732 doi:10.1016/s1094-9194(17)30099-3 — Carpenter's Exotic Animal Formulary 6th ed, Table 8.1 (Antimicrobial Agents Used in Hedgehogs). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds): '10-20 mg/kg IM, IV q8-12h360,555,736,840 | African grey parrots, Amazon parrots, cockatiels, cockatoos/PK'. Superscript 840 = Schroeder EC, Frazier DL, Morris PJ, et al. Pharmacokinetics of ticarcillin and amikacin in blue-fronted Amazon parrots (Amazona aestiva aestiva). J Avian Med Surg. 1997,11:260-267 - one of the four references on this row.
· Carpenter's Exotic Animal Formulary, 6th Ed — Carpenter's Exotic Animal Formulary, 6th ed, Table 4.1 (corpus PDF pp.212-215); located 2026-08-06 by chapter-governed table: this table is in the chapter covering this species and names this drug. NOTE: the served figure was matched against the table as a whole, not against this drug's own row, so confirm the number on the page before relying on it. The held copy has no printed page numbers, so the numbered table is the citable location. — CORROBORATED 2026-08-06 by independent literature: Amikacin pharmacokinetics and the effects of ambient temperature on the dosage regimen in ball pythons (Python regius). (Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 1997). PMID:9226620. https://pubmed.ncbi.nlm.nih.gov/9226620/. The paper reports this drug at this dose in this species: "perature on the dosage regimen in ball pythons (Python regius). The serum concentration of amikacin […]". This is a second source alongside the book already cited; it corroborates the figure and does not by itself establish that the dose is correct. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· Dorrestein GM. Antimicrobial drug use in companion birds. In: PrescottJF, Baggot JD, Walker RD, eds. Antimicrobial Therapy in Veterinary Medicine, 3rd ed., Iowa State University Press, Ames, IA; 2000:617-636. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· Dorrestein GM. Passerine and softbill therapeutics. Vet Clin North Am Exot Anim Pract. 2000;3:35-57. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.405 doi:10.1016/s1094-9194(17)30094-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· El-Gammal AA, Ravis WR, Krista LM, et al. Pharmacokinetics and intramuscular bioavailability of amikacin in chickens following single and multiple dosing. J Vet Pharmacol Therap. 1992;15:133-142. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.617 doi:10.1111/j.1365-2885.1992.tb01000.x — Carpenter's Exotic Animal Formulary 6th ed, Table 6.1 (Antimicrobial Agents Used in Backyard Poultry, Gamebirds, and Waterfowl.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Backyard Poultry Medicine and Surgery — ISBN 9781119511755, https://openlibrary.org/isbn/9781119511755
· Gronwall R, Brown MP, Clubb S. Pharmacokinetics of amikacin in African gray parrots. Am J Vet Res. 1989;50:250-252. doi:10.2460/ajvr.1989.50.02.250 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.405 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 5.1 (Antimicrobial Agents Used in Birds.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· Hiebert K, Knych H, Hawkins S. Subcutaneous amikacin administration in red-eared sliders (Trachemys scripta elegans) produces prolonged detectable plasma concentrations without biochemistry evidence of impaired renal function. Am J Vet Res. 2024;85(9):ajvr.24.03.0088. doi:10.2460/ajvr.24.03.0088https://europepmc.org/abstract/MED/38901454
· Mcclure JT, Rosin E. Comparison of amikacin dosing regimens in neutropenic guinea pigs with Escherichia coli infection. Am J Vet Res. 1998;59:750-755. doi:10.2460/ajvr.1998.59.06.750 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.770 (2026-08-01). — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.770 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.1 (Antimicrobial and Antifungal Agents Used in Rodents.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712; Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· Morrisey JK, Carpenter JW, et al. Formulary. In: Quesenberry KE, Orcutt CJ, Mans C, et al. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:620-630. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.703 — Carpenter's Exotic Animal Formulary 6th ed, Table 7.1 (Antimicrobial and Antifungal Agents Used in Sugar Gliders). Located 2026-08-05: the only table covering this species in which the drug's own row prints this dose. The copy held is an ebook conversion with no printed page numbers, so the table is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350
· Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted), Amikacin, Systemic, Dosages, printed p.50 (lookup p.77), entry a) under RABBITS: "8 - 16 mg/kg SC, IM, or IV daily dose (may be divided and given every 8-24 hours). Increased […]" Superscript 39 → Ivey E, Morrisey J. Therapeutics for rabbits. Vet Clin North Am Exotic Anim Pract. 2000;3(1):183-216 (resolved via plumbref). — Plumb's 10th ed (held) printed p.1341, Amikacin Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207
· Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted), p.76-77 — Amikacin, Systemic, Dosages, HORSES (adults) — Plumb's 10th ed (held) printed p.1341, Amikacin Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207
· Plumb's Veterinary Drug Handbook, 10th ed (held), Amikacin Systemic monograph, printed p.49 (corpus PDF p.76), DOGS - "Susceptible infections and empirical therapy (extra-label): 15 - 30 mg/kg IV, IM, SC once daily." [CORRECTED - the page previously named, printed p.1341, is Amikacin Ophthalmic and carries no systemic dose.] ISBN 9781394172207
· Plumb's Veterinary Drug Handbook, 10th ed (held), Amikacin Systemic monograph, printed p.50 (corpus PDF p.77), HORSES - treatment of septic joints, intra-articular. [CORRECTED - the page previously cited, printed p.1341, is the Amikacin Ophthalmic monograph and carries no intra-articular or equine figure.] ISBN 9781394172207
· Ramsey I, ed. BSAVA Small Animal Formulary, 10th ed. Part B: Exotic Pets. Gloucester: British Small Animal Veterinary Association; 2023. p.28. — LOCATOR CONVENTION 2026-08-07: the bare 'p.28' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.14; verified by finding the drug named there. If you are holding the book, turn to p.14. — SOURCE EDITION: BSAVA Small Animal Formulary, Part B — Exotic Pets — ISBN 9781910443712, https://openlibrary.org/isbn/9781910443712
· Ratliff CM, Zaffarano BA. Therapeutic use of regional limb perfusion in a chicken. J Avian Med Surg. 2017;31:29-32. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.617 — Carpenter's Exotic Animal Formulary 6th ed, Table 6.1 (Antimicrobial Agents Used in Backyard Poultry, Gamebirds, and Waterfowl.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Backyard Poultry Medicine and Surgery — ISBN 9781119511755, https://openlibrary.org/isbn/9781119511755
· Stahl SJ. Pet lizard conditions and syndromes. Semin Avian Exot Pet Med. 2003;12:162-182. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.212 — Carpenter's Exotic Animal Formulary 6th ed, Table 4.1 (Antimicrobial Agents Used in Reptiles.a,b). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929
· Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01). — Plumb's 10th ed (held) printed p.1341, Amikacin Ophthalmic monograph; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207