Which species have cited Amikacin dosing data?

Amikacin dosing in the ExoticRx formulary covers 8 species: African Grey Parrot, Amazon Parrot, Ball Python, Cat (Domestic), Dog (Domestic), Guinea Pig, Horse (Equine), Rabbit (Domestic).

Is Amikacin a controlled substance?

Amikacin is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Amikacin

US brand names:Amiglyde-V, Amikin

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Amikacin is dosed at 5 mg/kg IM q72h in ball pythons, per Carpenter's Exotic Animal Formulary, 6th Ed. Verify against current literature before clinical use.

Drug Class

Antibiotic

Routes

IVIMSC

Indications

Gram-negative infectionsGram-negative infections (Pasteurella)Gram-negative sepsispneumoniaSeptic arthritis (local)

Mechanism of Action

Irreversibly binds 30S ribosomal subunit, inhibiting bacterial protein synthesis. Concentration-dependent bactericidal activity.

Side effects & warnings

Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.

Evidence levels across 10 dose rules

Strong×4Moderate×4Weak×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 7 published sources

· Carpenter's Exotic Animal Formulary, 6th Ed
· Gronwall R, Brown MP, Clubb S. Pharmacokinetics of amikacin in African gray parrots. Am J Vet Res. 1989;50:250-252. doi:10.2460/ajvr.1989.50.02.250 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.405 (2026-08-01).
· Mcclure JT, Rosin E. Comparison of amikacin dosing regimens in neutropenic guinea pigs with Escherichia coli infection. Am J Vet Res. 1998;59:750-755. doi:10.2460/ajvr.1998.59.06.750 — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.770 (2026-08-01).
· Plumb's Veterinary Drug Handbook, 9th Ed
· Plumb's Veterinary Drug Handbook, 9th Ed, Amikacin, Systemic, Dosages, printed p.50 (lookup p.77), entry a) under RABBITS: "8 - 16 mg/kg SC, IM, or IV daily dose (may be divided and given every 8-24 hours). Increased efficacy and decreased toxicity are possible if given once daily." Superscript 39 → Ivey E, Morrisey J. Therapeutics for rabbits. Vet Clin North Am Exotic Anim Pract. 2000;3(1):183-216 (resolved via plumbref).

Sample dosing (2 of 10 cited rules)

A dog/cat sample is shown here. Cited dosing for all 8 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	SC	15–30 mg/kg	q24h	Strong	Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01).
Cat (Domestic)	IV	10–14 mg/kg	q24h	Strong	Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.76 (2026-08-01).

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Schroeder EC, Frazier DL, Morris PJ, et al. Pharmacokinetics of ticarcillin and amikacin in blue-fronted Amazon parrots (Amazona aestiva aestiva). J Avian Med Surg. 1997;11:260-267. — Verified against Carpenter's Exotic Animal Formulary, 6th Ed, p.405 (2026-08-01).