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Amikacin for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Amikacin is used in guinea pig for Gram-negative infections. Routes documented in guinea pig: SC. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Amikacin in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Amiglyde-V, Amikin

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
SC10–15 mg/kgq24h7-10 daysGram-negative infectionsWeakCarpenter's Exotic Animal Formulary, 6th Ed

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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Irreversibly binds 30S ribosomal subunit, inhibiting bacterial protein synthesis. Concentration-dependent bactericidal activity.

Side effects & warnings

Nephrotoxic and ototoxic. Monitor renal function (BUN, creatinine). Ensure adequate hydration. Avoid concurrent use with other nephrotoxic drugs. Neuromuscular blockade risk.

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with guinea pig dosing

Amikacin dosing in other species

Why a species-specific page? Amikacin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.