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Doxycycline for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Doxycycline is used in guinea pig for Respiratory infections, Bordetella bronchiseptica, Chlamydia caviae (conjunctivitis). Routes documented in guinea pig: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 3 cited dose rules for Doxycycline in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Vibramycin

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO2.5–5 mg/kgq12h10-14 daysRespiratory infectionsModerateCarpenter's Exotic Animal Formulary, 6th Ed
PO2.5–5 mg/kgq12h14-21 daysBordetella bronchisepticaModerateCarpenter's Exotic Animal Formulary, 6th Ed
PO5–10 mg/kgq12h14-21 daysChlamydia caviae (conjunctivitis)ModerateCarpenter's Exotic Animal Formulary, 6th Ed

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Mechanism of action

Inhibits protein synthesis by binding to 30S ribosomal subunit, preventing aminoacyl-tRNA attachment.

Side effects & warnings

Can cause esophageal strictures in cats if not followed by water. Photosensitivity. Avoid in pregnant animals (tooth discoloration in fetus).

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with guinea pig dosing

Doxycycline dosing in other species

Why a species-specific page? Doxycycline pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.