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Chloramphenicol for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Chloramphenicol is used in guinea pig for Bacterial infections. Routes documented in guinea pig: PO. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Chloramphenicol in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO30–50 mg/kgq12h7-14 daysBacterial infectionsModerateCarpenter's Exotic Animal Formulary, 6th Ed

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Mechanism of action

Binds to 50S ribosomal subunit, inhibiting peptidyl transferase and bacterial protein synthesis. Bacteriostatic.

Side effects & warnings

Human health hazard: wear gloves when handling (aplastic anemia risk in humans). May cause bone marrow suppression in cats. Monitor CBC during prolonged use.

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with guinea pig dosing

Chloramphenicol dosing in other species

Why a species-specific page? Chloramphenicol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.