Question 1

What is Doxycycline used for?

Accepted Answer

Doxycycline is indicated for: Anaplasmosis, atypical respiratory, atypicals, Bacterial infections, Bartonella (cat scratch disease), Bordetella bronchiseptica, Canine infectious respiratory disease complex (CIRD), Chlamydia caviae (conjunctivitis), Chlamydophila, Chlamydophila psittaci (non-compliant patients), Chlamydophila psittaci (psittacosis), CRD chronic suppression, Feline chronic gingivostomatitis adjunct, Feline stomatitis adjunct, Heartworm treatment adjunct (slow kill), Hemoplasma (Mycoplasma haemofelis), hospitalized patients, intracellular infections, Lawsonia intracellularis, Leptospirosis (elimination phase), Lyme, Lyme disease, Mycoplasma, Pasteurella, Pasteurella multocida, respiratory, respiratory infections, Rocky Mountain Spotted Fever, Severe tick-borne disease, snuffles, Tick-borne diseases, Upper respiratory infections.

Question 2

What routes can Doxycycline be administered by?

Accepted Answer

Available routes: PO, IV.

Question 3

Which species have cited Doxycycline dosing data?

Accepted Answer

Doxycycline dosing in the ExoticRx formulary covers 13 species: African Grey Parrot, African Pygmy Hedgehog, Ball Python, Bearded Dragon, Cat (Domestic), Cattle (Beef/Dairy), Chinchilla, Dog (Domestic), Ferret, Guinea Pig, Horse (Equine), Pet Rat, Rabbit (Domestic).

Question 4

Is Doxycycline a controlled substance?

Accepted Answer

Doxycycline is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Doxycycline?

Accepted Answer

Can cause esophageal strictures in cats if not followed by water. Photosensitivity. Avoid in pregnant animals (tooth discoloration in fetus).

Question 6

What are the side effects of Doxycycline?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Doxycycline: Can cause esophageal strictures in cats if not followed by water. Photosensitivity. Avoid in pregnant animals (tooth discoloration in fetus).

Question 7

How does Doxycycline work?

Accepted Answer

Inhibits protein synthesis by binding to 30S ribosomal subunit, preventing aminoacyl-tRNA attachment.

Species	Route	Dose	Frequency	Evidence	Source
Cat (Domestic)	PO	5–10 mg/kg	q12-24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)	PO	5–10 mg/kg	q12-24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Doxycycline

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Doxycycline dosing data (29 dose rules)

Evidence levels across 29 dose rules

Backed by 9 published sources

Sample dosing (2 of 29 cited rules)

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