ExoticRx · exoticrx.com/drugs/ampicillin
Ampicillin
Polyflex
Drug Class
Routes
Indications
Mechanism of Action
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Broader spectrum than penicillin G with gram-negative coverage.
Side effects & warnings
CONTRAINDICATED in rabbits, guinea pigs, and hamsters (fatal dysbiosis). May cause GI upset. Cross-reactivity with other beta-lactams. IM injection may be painful.
Species with Ampicillin dosing data (9 dose rules)
Species references:All African Grey Parrot drugsAll Cat (Domestic) drugsAll Cattle (Beef/Dairy) drugsAll Dog (Domestic) drugsAll Horse (Equine) drugsAll Swine (Pig) drugs
Evidence levels across 9 dose rules
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
Backed by 3 published sources
- · Carpenter's Exotic Animal Formulary, 6th Ed
- · Plumb's Veterinary Drug Handbook
- · Plumb's Veterinary Drug Handbook, 9th Ed
Sample dosing (2 of 9 cited rules)
A dog/cat sample is shown here. Cited dosing for all 6 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansArticles mentioning Ampicillin
- Antibiotic Selection in Exotic Animals: Principles and PitfallsHow to choose an antibiotic for rabbits, guinea pigs, parrots, and reptiles — with the species-specific contraindications general practice reaches for first by reflex.
- Rabbit Drug Dosing: A Vet's Quick ReferenceAntibiotic, analgesic, and antiparasitic dosing for domestic rabbits — and the oral antibiotics you must never reach for.
More Antibiotic drugs
Source citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.