Rabbit (Domestic)

Clinical context for rabbit dosing

Rabbits (Oryctolagus cuniculus) are obligate hindgut fermenters where oral β-lactams (penicillins, oral cephalosporins, clindamycin, oral macrolides) reliably cause fatal Clostridium spiroforme enterotoxaemia. This single rule eliminates the largest empiric antimicrobial options and pushes practice toward fluoroquinolones, sulfonamides, and parenteral β-lactams when indicated. GI stasis is a clinical emergency requiring prokinetics, analgesia, and aggressive supportive care; buprenorphine is the standard analgesic with notably good species tolerance. Encephalitozoon cuniculus is endemic — fenbendazole 28-day courses are standard.